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3.A.1.201.51
Multidrug resistance protein 1, ABCB1, of 495 aas and 6 TMSs in a 2 + 2 + 2 TMS arrangement. This system confers triclabendazole resistance in Fasciola hepatica and shows dominant inheritance (Beesley et al. 2023).

Accession Number:THD20368
Protein Name:THD20368.1 Multidrug resistance protein 1 [Fasciola hepatica]
Length:496
Molecular Weight:
Species:Fasciola hepatica [6192]
Number of TMSs:7
Substrate drug

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MRSYRNQPSD NDPILKTKSG VSPEDPPVSF TGLFRYADGK DTTCVVFGII LFAAVGLSLP 
61:	LNTYFFRDEI NKFLLPTFTE NAAQTIVIQF SCLGAAVFVV AFAASALLDI SSKRQLHRIR 
121:	LKYFKAVLRQ DIPWFDERSS GELIGKLSDC IDTIELGIGK KIGEFFQNIT GFLAGIIIAF 
181:	YVGWKLTLVA CCTLPVVAAV FIAFAFVMKI FTRKEILAYA RAGSISGEVF TAVRTIVAFG 
241:	GEKKELDRYT QELSKAEKVG IQKSLAVGGV DGCIGLSVYS AAALIFWYGF RLIDTEGYDA 
301:	GSVVLVFINI LLGSIFLGNA LPSMQYFLSA KTAAQNIYGT IERVPPIDKD GEGVILNNFH 
361:	GNIQFQNVSF VYPTRPEVKI LENFNLTLKS GQTVALVGPS GSGKSTIVHM LQRYYDAAAG 
421:	NILIEGTDIC ELDLKAYRAQ IGCVQQEPIL FEGTIADNIR MGKLDATEEE IEEAAKKANA 
481:	HEFISNLPEV VLVIA