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|---|---|
| Accession Number: | Q9LJX0 |
| Protein Name: | Multidrug resistance protein 11 aka Pgp19 |
| Length: | 1252 |
| Molecular Weight: | 136788.00 |
| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
| Number of TMSs: | 12 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | auxin |
Cross database links:
| RefSeq: | NP_189528.1 |
|---|---|
| Entrez Gene ID: | 822519 |
| Pfam: | PF00664 PF00005 |
| KEGG: | ath:AT3G28860 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0005524
F:ATP binding
GO:0042626
F:ATPase activity, coupled to transmembrane m...
GO:0010329
F:auxin efflux transmembrane transporter acti...
GO:0005515
F:protein binding
GO:0010541
P:acropetal auxin transport
GO:0043481
P:anthocyanin accumulation in tissues in resp...
GO:0009734
P:auxin mediated signaling pathway
GO:0010540
P:basipetal auxin transport
GO:0048527
P:lateral root development
GO:0009640
P:photomorphogenesis
GO:0009958
P:positive gravitropism
GO:0008361
P:regulation of cell size
GO:0009637
P:response to blue light
GO:0010218
P:response to far red light
GO:0048443
P:stamen development
GO:0055085
P:transmembrane transport
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References (9)[1] “Multidrug resistance-like genes of Arabidopsis required for auxin transport and auxin-mediated development.” Noh B.et.al. 11701880 [2] “Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC clones.” Kaneko T.et.al. 10907853 [3] “Functional annotation of a full-length Arabidopsis cDNA collection.” Seki M.et.al. 11910074 [4] “PGP4, an ATP binding cassette P-glycoprotein, catalyzes auxin transport in Arabidopsis thaliana roots.” Terasaka K.et.al. 16243904 [5] “The Arabidopsis thaliana ABC protein superfamily, a complete inventory.” Sanchez-Fernandez R.et.al. 11346655 [6] “TWISTED DWARF1, a unique plasma membrane-anchored immunophilin-like protein, interacts with Arabidopsis multidrug resistance-like transporters AtPGP1 and AtPGP19.” Geisler M.et.al. 14517332 [7] “Two homologous ATP-binding cassette transporter proteins, AtMDR1 and AtPGP1, regulate Arabidopsis photomorphogenesis and root development by mediating polar auxin transport.” Lin R.et.al. 15908594 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MSETNTTDAK TVPAEAEKKK EQSLPFFKLF SFADKFDYLL MFVGSLGAIV HGSSMPVFFL 61: LFGQMVNGFG KNQMDLHQMV HEVSRYSLYF VYLGLVVCFS SYAEIACWMY SGERQVAALR 121: KKYLEAVLKQ DVGFFDTDAR TGDIVFSVST DTLLVQDAIS EKVGNFIHYL STFLAGLVVG 181: FVSAWKLALL SVAVIPGIAF AGGLYAYTLT GITSKSRESY ANAGVIAEQA IAQVRTVYSY 241: VGESKALNAY SDAIQYTLKL GYKAGMAKGL GLGCTYGIAC MSWALVFWYA GVFIRNGQTD 301: GGKAFTAIFS AIVGGMSLGQ SFSNLGAFSK GKAAGYKLME IINQRPTIIQ DPLDGKCLDQ 361: VHGNIEFKDV TFSYPSRPDV MIFRNFNIFF PSGKTVAVVG GSGSGKSTVV SLIERFYDPN 421: SGQILLDGVE IKTLQLKFLR EQIGLVNQEP ALFATTILEN ILYGKPDATM VEVEAAASAA 481: NAHSFITLLP KGYDTQVGER GVQLSGGQKQ RIAIARAMLK DPKILLLDEA TSALDASSES 541: IVQEALDRVM VGRTTVVVAH RLCTIRNVDS IAVIQQGQVV ETGTHEELIA KSGAYASLIR 601: FQEMVGTRDF SNPSTRRTRS TRLSHSLSTK SLSLRSGSLR NLSYSYSTGA DGRIEMISNA 661: ETDRKTRAPE NYFYRLLKLN SPEWPYSIMG AVGSILSGFI GPTFAIVMSN MIEVFYYTDY 721: DSMERKTKEY VFIYIGAGLY AVGAYLIQHY FFSIMGENLT TRVRRMMLSA ILRNEVGWFD 781: EDEHNSSLIA ARLATDAADV KSAIAERISV ILQNMTSLLT SFIVAFIVEW RVSLLILGTF 841: PLLVLANFAQ QLSLKGFAGD TAKAHAKTSM IAGEGVSNIR TVAAFNAQSK ILSLFCHELR 901: VPQKRSLYRS QTSGFLFGLS QLALYGSEAL ILWYGAHLVS KGVSTFSKVI KVFVVLVITA 961: NSVAETVSLA PEIIRGGEAV GSVFSVLDRQ TRIDPDDADA DPVETIRGDI EFRHVDFAYP 1021: SRPDVMVFRD FNLRIRAGHS QALVGASGSG KSSVIAMIER FYDPLAGKVM IDGKDIRRLN 1081: LKSLRLKIGL VQQEPALFAA TIFDNIAYGK DGATESEVID AARAANAHGF ISGLPEGYKT 1141: PVGERGVQLS GGQKQRIAIA RAVLKNPTVL LLDEATSALD AESECVLQEA LERLMRGRTT 1201: VVVAHRLSTI RGVDCIGVIQ DGRIVEQGSH SELVSRPEGA YSRLLQLQTH RI