3.A.1.205.21
ABC1 transporter. Excretes secondary metabolites such as terpenes. Involved in both
constitutive and jasmonic acid-dependent induced defense. Secretes the terpenes, sclareol and sclareolide and thereby confers resistance to the fungus, B.cinerea (Stukkens et al. 2005). Induced by sclareolide and sclareol, and by some phytohormones
such as jasmonic acid (JA) and ethylene. Strongly induced by compatible
pathogens such as B. cinerea and the bacterium, Pseudomonas syringae pv
tabaci, as well as by non pathogenic bacteria such as P. fluorescens, and
P. marginalis pv marginalis (Grec et al. 2003).
|
| Accession Number: | Q949G3 |
|---|
| Protein Name: | Pleiotropic drug resistance protein 1 |
|---|
| Length: | 1436 |
|---|
| Molecular Weight: | 161849.00 |
|---|
| Species: | Nicotiana plumbaginifolia (Leadwort-leaved tobacco) [4092] |
|---|
| Number of TMSs: | 16 |
|---|
| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
|---|
| Substrate |
terpene, sclareol, metabolite |
|---|
1: MEPADLSNLR GRSLRASIRG SMRGSIRENS NSIWRNNGAE VFSRSARDED DEEALKWAAL
61: EKLPTYDRLR KGILFGSQGA AAEVDVDDSG VLERKNLLER LVKVADEDNE KFLLKLKNRI
121: DRVGIDFPSI EVRFEHLNID ADAYVGSRAL PTFTNFISNF VEGLLDSIHI LPSKKRQVTI
181: LKDVSGIVKP CRMTLLLGPP GSGKTTLLLA LAGKLDSALK VTGKVTYNGH ELHEFVPQRT
241: AAYISQHDLH IGEMTVRETL EFSARCQGVG SRYEMLAELS RREKAANIKP DADIDMFMKA
301: ASTEGQEAKV VTDYILKILG LDICADTMVG DQMIRGISGG QKKRVTTGEM IVGPSKALFM
361: DEISTGLDSS TTYSIVNSLK QSVRIMKGTA LISLLQPAPE TYNLFDDIIL LSDGYIVYEG
421: PREEVLEFFE SMGFKCPERK GAADFLQEVT SKKDQQQYWI RRDEPYRFIT SKEFAEAYQS
481: FHVGRKVSDE LKTTFDKSKS HPAALTTQKY GIGKRQLLKV CTERELLLMQ RNSFVYLFKF
541: FQLLIIALMT MTIFFRTKMP RDSAEDGGIY SGALFFVVIM IMFNGLSELP MTLYKLPVFY
601: KQRDFLFYPS WAYAIPSWIL KIPVTFAEVG MWVFLTYYVM GFDPNVGRFF KQFLLLLLVN
661: QMASALFRFI AAVGRTMGVA STFGAFALLL QFALGGFILA RNDVKDWWIW GYWTSPLMYS
721: VNAILVNEFD GQKWKHIVAG GTEPLGAAVV RARGFFPDAY WYWIGVGALA GFIVMFNIAY
781: SVALAYLNPF DKPQATISDE SENNESESSP QITSTQEGDS ASENKKKGMV LPFDPHSITF
841: DEVVYSVDMP PEMRESGTSD NRLVLLKSVS GAFRPGVLTA LMGVSGAGKT TLMDVLAGRK
901: TGGYIDGSIK ISGYPKKQDT FARISGYCEQ NDIHSPYVTV FESLVYSAWL RLPQDVNEEK
961: RMMFVEEVMD LVELTPLRSA LVGLPGVNGL STEQRKRLTI AVELVANPSI IFMDEPTSGL
1021: DARAAAIVMR AVRNTVDTGR TVVCTIHQPS IDIFEAFDEL FLMKRGGQEI YVGPLGRQSC
1081: HLIKYFESIP GVSKIVEGYN PATWMLEVTA SSQEMALGVD FTDLYKKSDL YRRNKALIDE
1141: LSVPRPGTSD LHFDSEFSQP FWTQCMACLW KQHWSYWRNP AYTAVRLIFT TFIALIFGTM
1201: FWDIGTKVSR NQDLVNAMGS MYAAVLFLGV QNSSSVQPVV SVERTVFYRE KAAGMYSAIP
1261: YAFAQVLIEI PYIFVQATVY GLIVYSMIGF EWTVAKFFWD FFFMFFTFLY FTFFGMMTVA
1321: VTPNQNVASI VAGFFYTVWN LFSGFIVPRP RIPIWWRWYY WGCPIAWTLY GLVASQFGDL
1381: QDPLTDQNQT VEQFLRSNFG FKHDFLGVVA AVIVAFAVVF AFTFALGIKA FNFQRR