3.A.1.205.25
Plasma membrane ABCG1 or PDR1a of 1434 aas and 12 TMSs. 85% identical to TC# 3.A.1.205.21. PDR1 secretes plastid-produced diterpene(s) that are the antimicrobial compounds active in preinvasion defense, as well as the sesquiterpenoid, capsidiol, the major phytoalexin produced by Nicotiana and Capsicum species. Capsidiol is produced in plant tissues attacked by pathogens and plays a
major role in postinvasion defense by inhibiting pathogen growth (Shibata et al. 2016). This protein and ABCG2/PDR2, a close paralogue, export the same compounds and are essential for resistance to the potato late blight pathogen Phytophthora infestans. Thus, ABCG1/2 are involved in the export of both antimicrobial diterpene(s)
for preinvasion defense and capsidiol for postinvasion defense against
P. infestans.
|
| Accession Number: | BAR94041 |
|---|
| Protein Name: | BAR94041.1 PDR-type ACB transporter [Nicotiana benthamiana] |
|---|
| Length: | 1435 |
|---|
| Molecular Weight: | |
|---|
| Species: | Nicotiana benthamiana [4100] |
|---|
| Number of TMSs: | 13 |
|---|
| Substrate |
capsidiol, sesquiterpenoid, diterpene |
|---|
1: MEPANLSNLR GSSLRGSMRG SLRANSNSIW RNNGVEIFSR SSRDEDDEEA LKWAALEKLP
61: TFDRLRKGLL FGSQGAAAEV DINDLGFQER KNLLERLVKV ADEDNEKFLL KLKNRIDRVG
121: IDLPTIEVRY EHLNIDADAY VGSRGLPTFM NFMTNFVETL LNSLHILPSR KRQLTILKDI
181: SGIIKPCRMT LLLGPPSSGK TTLLLALAGK LDPALKVTGK VSYNGHELHE FVPQRTAAYI
241: SQHDLHIGEM TVRETLEFSA RCQGVGSRFE MLAELSRREK AANIKPDADI DVYMKAAATE
301: GQEANVVTDY VLKILGLDIC ADTMVGDDMI RGISGGQKKR VTTGEMLVGP SKALFMDEIS
361: TGLDSSTTYS IVNSLRQSVQ ILKGTAVISL LQPAPETYNL FDDIILLSDG YIVYQGPRDD
421: VLEFFESMGF KCPHRKGVAD FLQEVTSKKD QQQYWSKRNE PYRFITSKEF AEAYQSFHVG
481: RKLGDELATP FDKTKCHPAA LTNEKYGIGK KELLKVCTER ELLLMKRNSF VYMFKFSQLT
541: IMALITMTLF FRTEMPRDTT DDGAIYAGAL FFVVIMIMFN GMSELAMTIF KLPVFYKQRD
601: LLFFPSWAYA IPSWILKIPV TLVEVGLWVI LTYYVIGFDP NITRFLKQFL LLIVVNQMAS
661: GLFRFIGAVG RTMGVASTFG SFALLLQFAL GGFVLSRDDV KSWWIWGYWT SPMMYSVNSI
721: LVNEFDGKKW NHIVPGGNET LGATVVKSRG FFPEAYWYWI GVGALVGFTV VFNFCYSVAL
781: AYLNPFDKPQ AVLAEDGENA ENVEVSSQIT STDGGDSISE SQNNKKGMVL PFEPHSITFD
841: DVVYSVDMPQ EMKEQGAGQD RLVLLKGVSG AFRPGVLTAL MGVSGAGKTT LMDVLAGRKT
901: GGYIDGEIKI SGYPKKQETF ARISGYCEQN DIHSPYVTVY ESLVYSAWLR LPQDVDEKTR
961: KMFVDEVMEL VELGPLRSAL VGLPGVNGLS TEQRKRLTIA VELVANPSII FMDEPTSGLD
1021: ARAAAIVMRT VRNTVDTGRT VVCTIHQPSI DIFEAFDELF LMKRGGQEIY VGPLGRHSCH
1081: LIKYFESNPG VAKIKEGYNP ATWMLEVTAS AQEMLLGVDF TEVYKNSDLY RSNKALISEL
1141: GVPRPGSKDL HFETQYSQSF WTQCMACLWK QHWSYWRNPA YTAVRFIFTT FIALIFGTMF
1201: WDLGTKVSES QDLLNAMGSM YAAVLFLGVQ NASSVQPVVA VERTVFYRER AAGMYSAIPY
1261: AFGQVAIEIP YIFVQSVFYG IIVYAMIGFE WDVGKFFWYL FIMFFTLLYF TFYGMMSVAV
1321: TPNQNVASIV AAFFYGVWNL FSGFIIPRPR MPVWWRWYYW ANPVAWTLYG LVASQFGDIQ
1381: TKLSDNETVK QFLRRFFGFR HDFLGVVAAV LSAYVFVFAF TFAFAIKAFN FQRR