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Accession Number: | P78595 |
Protein Name: | Cdr2 |
Length: | 1499 |
Molecular Weight: | 168893.00 |
Species: | Candida albicans (Yeast) [5476] |
Number of TMSs: | 11 |
Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
Substrate | caspofungin, amorolfine, 1H-pyrrole, terbinafine, antifungal agent |
Cross database links:
Pfam: | PF01061 PF00005 PF06422 |
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Gene Ontology
GO:0016021
C:integral to membrane
GO:0005524
F:ATP binding
GO:0042626
F:ATPase activity, coupled to transmembrane m...
GO:0006810
P:transport
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References (1)[1] “Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene.” Sanglard D.et.al. 9043118
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External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MSTANTSLSQ QLDENPWVDA SDNSSVQEYQ GFDATASHNI QDLARKLTHG STNGDHHSAN 61: DLARYLSHMS DIPGVSPFNG NISHEQLDPD SENFNAKYWV KNLKKLFESD SDYYKPSKLG 121: VAYRNLRAYG IANDSDYQPT VTNALWKFTT EAINKLKKPD DSKYFDILKS MDAIMRPGEL 181: TVVLGRPGAG CSTLLKTIAV NTYGFHIGKE SQITYDGLSP HDIERHYRGD VIYSAETDVH 241: FPHLSVGDTL EFAARLRTPQ NRGEGIDRET YAKHMASVYM ATYGLSHTRN TNVGNDFVRG 301: VSGGERKRVS IAEASLSGAN IQCWDNATRG LDSATALEFI RALKTSATIL DTTPLIAIYQ 361: CSQDAYELFD NVVVLYEGYQ IFFGKASKAK EYFENMGWKC PQRQTTADFL TSLTNPAERE 421: PLPGYEDKVP RTAQEFETFW KNSPEYAELT KEIDEYFVEC ERSNTGETYR ESHVGKQSNN 481: TRPSSPYTVS FFMQVRYVIA RNFLRMKGDP SIPLISILSQ LVMGLILASV FFNLRKSTDT 541: FYFRGGALFF SVLFNAFSSL LEILSLYEAR PIVEKHRKYA LYRPSADALA SIISELPVKL 601: LMTMSFNIVY YFMVNLRRTA GNFFFYWLMC ASCTLVMSHM FRSIGAVTTT IATAMSLSTV 661: FLLAMIIYAG FVLPIPYILG WSRWIRYINP VTYIFESLMV NEFHGREFEC GQYIPSGPGF 721: ENLPVENKVC TTVGSTPGST VVQGTEYIKL AYQFYSSHKW RNFGITVAFA VFFLGVYVAL 781: TEFNKGASQK GEIVLFLKGS LKKHKRKTAA SNKGDIEAGP VAGKLDYQDE AEAVNNEKFT 841: EKGSTGSVDF PENREIFFWR DLTYQVKIKK EDRVILDHVD GWVKPGQITA LMGASGAGKT 901: TLLNCLSERV TTGIITDGER LVNGHALDSS FQRSIGYVQQ QDVHLETTTV REALQFSAYL 961: RQSNKISKKE KDDYVDYVID LLEMTDYADA LVGVAGEGLN VEQRKRLTIG VELVAKPKLL 1021: LFLDEPTSGL DSQTAWSICK LMRKLADHGQ AILCTIHQPS ALIMAEFDKL LFLQKGGRTA 1081: YFGELGENCQ TMINYFEKYG ADPCPKEANP AEWMLQVVGA APGSHAKQDY FEVWRNSSEY 1141: QAVREEINRM EAELSKLPRD NDPEALLKYA APLWKQYLLV SWRTIVQDWR SPGYIYSKLI 1201: LVISSSLFIG FSFFKSKNNL QGLQSQMLAV FMFFVPFTTF IDQMLPYFVK HRAVYEVREA 1261: PSRTFSWFAF IAGQITSEIP FQIVVGTISY FCWYYPVGLY ANAEPTDSVN SRGVLMWMLL 1321: TAFYVYTSTM GQLAISLNEL IDNAANLATT LFTLCLMFCG VLAGPNVIPG FWIFMYRCNP 1381: FTYLIQAILS TGLANAKVTC APRELVTLKP PMGETCSSFI GPYTEAAGGY FSTNSDGTCS 1441: VCRIDSTNQF LESINALFSQ RWRNFGIFVA FIGINIILTI FFYWLARVPK GNREKKMKK