3.A.1.212.3
ABC-type MDR2 of 802 aas and 6 TMSs. Exports many drugs including antifungal agents (Martins et al. 2016).
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| Accession Number: | F2RYR3 |
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| Protein Name: | ABC multidrug transporter Mdr2 |
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| Length: | 802 |
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| Molecular Weight: | 86423.00 |
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| Species: | Trichophyton tonsurans (strain CBS 112818) (Scalp ringworm fungus) [647933] |
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| Number of TMSs: | 6 |
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| Substrate |
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1: MRGSRVLQTA SFSRDAVRCS PLGLNLSSRC LATDSRAPLV HPTAFSRQYH AVSLLVLGGN
61: RLHRCGIFTH ASCPDVLGKL SRNAVIPQPT NLIYRQLRFA TGKSSLGENG SSQLQESTAP
121: VVKEVAQAEE ISQAFERSER ASQAAQINLS ARLAKDGLAS GKKSGLREIW RLITIARPEA
181: KVLSVAFLFL LISSSVAMSI PFSIGKILDI ATSSNPNALK DFLGISLPVF YTALGGIILL
241: GAAANYGRII ILRIVGERIV ARLRAKLFRN TFVQDAEFFD ANRVGDLISR LSSDTIIVGK
301: SITQNLSDGL RAAVSGAAGF GMMAYVSLKL SSVLALLFPP IALAAFFYGR AIRNLSRKIQ
361: KNVGTLTKIA EDRVVIVKTS QSFAGEILEV HRYNRQVKRI FELGKKESFI SATFFSGTSL
421: MGNATILALL YVGGGMVQSQ AISIGELTSF LMYTAYAGSS LFGLSSFYSE LMKGAGAASR
481: LFELQDRRPK ISPTAGDKVT SARGPIRFKN VAFSYPTRPA VTIFKDLDFE IPQGSNVAIV
541: GPSGGGKSTI ASLLLRFYSP TQGQVFINGK DVATMNAKSL RRKIGIVAQE PVLFSGSIAE
601: NISYGKPDAT RSQIIAAARK ANCQFISDFP DGLDTNVGPK GAQLSGGQKQ RIAIARALIK
661: EPDILILDEA TSALDAESET LVNSALAALL RENNTTISIA HRLSTIKRSD TIIVLDSEGK
721: VAEMGSYNDL NSRPDGAFTK LMAWQLSGGE GITAPVHNKP ISRGPPSETE HLQQLLQEGE
781: DEEYDEAETE DEPRSTDEIE KK