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4.A.1.2.4 Trehalose porter, TreB (IIBC) which can take up maltose by facilitated diffusion (Decker et al. 1999). Can also transport sucrose at a low rate (Steen et al. 2014).
Accession Number:	P36672
Protein Name:	PTTB aka TREB aka B4240
Length:	473
Molecular Weight:	51081.00
Species:	Escherichia coli [83333]
Number of TMSs:	11
Location¹ / Topology² / Orientation³:	Cell inner membrane¹ / Multi-pass membrane protein²
Substrate	alpha,alpha-trehalose

RefSeq:	AP_004738.1 NP_418661.1
Entrez Gene ID:	948761
Pfam:	PF00367 PF02378
BioCyc:	EcoCyc:TREB-MONOMER ECOL168927:B4240-MONOMER
KEGG:	ecj:JW4199 eco:b4240
Gene Ontology GO:0016021 C:integral to membrane GO:0005886 C:plasma membrane GO:0016301 F:kinase activity GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosph... GO:0005351 F:sugar:hydrogen symporter activity GO:0015574 F:trehalose transmembrane transporter activity GO:0009401 P:phosphoenolpyruvate-dependent sugar phospho... GO:0015771 P:trehalose transport
References (5) [1] “Molecular analysis of treB encoding the Escherichia coli enzyme II specific for trehalose.” Klein W.et.al. 7608078 [2] “Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes.” Burland V.D.et.al. 7610040 [3] “The complete genome sequence of Escherichia coli K-12.” Blattner F.R.et.al. 9278503 [4] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.” Hayashi K.et.al. 16738553 [5] “Global topology analysis of the Escherichia coli inner membrane proteome.” Daley D.O.et.al. 15919996

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MMSKINQTDI DRLIELVGGR GNIATVSHCI TRLRFVLNQP ANARPKEIEQ LPMVKGCFTN 
61:	AGQFQVVIGT NVGDYYQALI ASTGQAQVDK EQVKKAARHN MKWHEQLISH FAVIFFPLLP 
121:	ALISGGLILG FRNVIGDLPM SNGQTLAQMY PSLQTIYDFL WLIGEAIFFY LPVGICWSAV 
181:	KKMGGTPILG IVLGVTLVSP QLMNAYLLGQ QLPEVWDFGM FSIAKVGYQA QVIPALLAGL 
241:	ALGVIETRLK RIVPDYLYLV VVPVCSLILA VFLAHALIGP FGRMIGDGVA FAVRHLMTGS 
301:	FAPIGAALFG FLYAPLVITG VHQTTLAIDL QMIQSMGGTP VWPLIALSNI AQGSAVIGII 
361:	ISSRKHNERE ISVPAAISAW LGVTEPAMYG INLKYRFPML CAMIGSGLAG LLCGLNGVMA 
421:	NGIGVGGLPG ILSIQPSYWQ VFALAMAIAI IIPIVLTSFI YQRKYRLGTL DIV

4.A.1.2.4
Trehalose porter, TreB (IIBC) which can take up maltose by facilitated diffusion (Decker et al. 1999). Can also transport sucrose at a low rate (Steen et al. 2014).

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

4.A.1.2.4Trehalose porter, TreB (IIBC) which can take up maltose by facilitated diffusion (Decker et al. 1999). Can also transport sucrose at a low rate (Steen et al. 2014).

Cross database links:

Gene Ontology

References (5)

External Searches:

Analyze:

4.A.1.2.4
Trehalose porter, TreB (IIBC) which can take up maltose by facilitated diffusion (Decker et al. 1999). Can also transport sucrose at a low rate (Steen et al. 2014).