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4.A.6.1.11
Mannose enzyme II complex, IIAB, IIC, IID. IIC/IID serve allows entry of some bacteriocins including pediocin (class IIa), lactococcin A and lactococcin Z (class IIc) (Kjos et al., 2011; Daba et al. 2018). Transports and phosphorylates Glucose, Mannose and Glucosamine.  The IID component is the probably receptor for several bacteriocins, subclass IIa bacteriocins (pediocin-like; pediocins) and subclass IId ones - lactococcin A (LcnA), lactococcin B (LcnB), garvicin Q (GarQ), and garvicins A, B and C (GarA-C) (Tymoszewska et al. 2018). Individual amino acids localized mostly in the sugar channel-forming transmembrane parts of subunit IIC or in the extracellular parts of IID likely are involved in the interaction with each bacteriocin, and these have been specified (Tymoszewska et al. 2018).

Accession Number:D2BKY7
Protein Name:Mannose-specificPTS system, IIAB component
Length:329
Molecular Weight:35064.00
Species:Lactococcus lactis subsp. lactis (strain KF147) [684738]
Substrate mannose

Cross database links:

Entrez Gene ID: 8679299   
Pfam: PF03610    PF03830   
KEGG: llk:LLKF_1868   

Gene Ontology

GO:0005737 C:cytoplasm
GO:0016021 C:integral to membrane
GO:0008982 F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GO:0009401 P:phosphoenolpyruvate-dependent sugar phosphotransferase system

References (2)

[1] “Genome-scale genotype-phenotype matching of two Lactococcus lactis isolates from plants identifies mechanisms of adaptation to the plant niche.”  Siezen R.J.et.al.   18039825
[2] “Complete genome sequence of Lactococcus lactis subsp. lactis KF147, a plant-associated lactic acid bacterium.”  Siezen R.J.et.al.   20348266

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSIGIVIASH GEFAAGIKQS GSMIFGEQEK VQVVTFMPSE GPTDLHAKIE AAIATFDAED 
61:	EVLVLADLWS GSPFNQASAV MGENPERKIA IITGLNLPML IQAYTERMMD ASAGVDKVVA 
121:	NIMKEAKGGI KVLPEELQPA EETAVAAAPA AVQGAIPEGT VIGDGKIKIN LARIDSRLLH 
181:	GQVATAWTPD SRANRIIVVS DTVSKDELRK KLIEQAAPTG VKANVIPIKK MIEVAKDPRF 
241:	GDTKALLLFE TPQDALATIE GGVPIETLNV GSMAHSTGKT MLNKVLSMDK DDVATFEKLR 
301:	DLGVKFDVRK VPADSKSDLF GLINKADVQ