| |
---|---|
Accession Number: | Q96PH1 |
Protein Name: | Nox5 |
Length: | 765 |
Molecular Weight: | 86439.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 7 |
Location1 / Topology2 / Orientation3: | Membrane1 / Multi-pass membrane protein2 |
Substrate | electron |
Cross database links:
RefSeq: | NP_078781.2 |
---|---|
Entrez Gene ID: | 79400 |
Pfam: | PF08022 PF01794 PF08030 |
OMIM: |
606572 gene |
KEGG: | hsa:79400 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005509
F:calcium ion binding
GO:0009055
F:electron carrier activity
GO:0050660
F:FAD binding
GO:0020037
F:heme binding
GO:0015252
F:hydrogen ion channel activity
GO:0050661
F:NADP or NADPH binding
GO:0016175
F:superoxide-generating NADPH oxidase activity
GO:0008283
P:cell proliferation
GO:0050663
P:cytokine secretion
GO:0000910
P:cytokinesis
GO:0022900
P:electron transport chain
GO:0006917
P:induction of apoptosis
GO:0006811
P:ion transport
GO:0043012
P:regulation of fusion of sperm to egg plasma...
GO:0010155
P:regulation of proton transport
GO:0042554
P:superoxide anion generation
| |
References (8)[1] “A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes.” Banfi B.et.al. 11483596 [2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [3] “Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation.” Kawahara T.et.al. 15994299 [4] “Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5.” Cheng G.et.al. 11376945 | |
Structure: | |
External Searches:
|
Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
|
1: MNTSGDPAQT GPEGCRGTMS AEEDARWLRW VTQQFKTIAG EDGEISLQEF KAALHVKESF 61: FAERFFALFD SDRSGTITLQ ELQEALTLLI HGSPMDKLKF LFQVYDIDVC ARQGASAGTE 121: WGAGAGPHWA SSPLGTGSGS IDPDELRTVL QSCLRESAIS LPDEKLDQLT LALFESADAD 181: GNGAITFEEL RDELQRFPGV MENLTISAAH WLTAPAPRPR PRRPRQLTRA YWHNHRSQLF 241: CLATYAGLHV LLFGLAASAH RDLGASVMVA KGCGQCLNFD CSFIAVLMLR RCLTWLRATW 301: LAQVLPLDQN IQFHQLMGYV VVGLSLVHTV AHTVNFVLQA QAEASPFQFW ELLLTTRPGI 361: GWVHGSASPT GVALLLLLLL MFICSSSCIR RSGHFEVFYW THLSYLLVWL LLIFHGPNFW 421: KWLLVPGILF FLEKAIGLAV SRMAAVCIME VNLLPSKVTH LLIKRPPFFH YRPGDYLYLN 481: IPTIARYEWH PFTISSAPEQ KDTIWLHIRS QGQWTNRLYE SFKASDPLGR GSKRLSRSVT 541: MRKSQRSSKG SEILLEKHKF CNIKCYIDGP YGTPTRRIFA SEHAVLIGAG IGITPFASIL 601: QSIMYRHQKR KHTCPSCQHS WIEGVQDNMK LHKVDFIWIN RDQRSFEWFV SLLTKLEMDQ 661: AEEAQYGRFL ELHMYMTSAL GKNDMKAIGL QMALDLLANK EKKDSITGLQ TRTQPGRPDW 721: SKVFQKVAAE KKGKVQVFFC GSPALAKVLK GHCEKFGFRF FQENF