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8.A: Auxiliary transport proteins
Auxiliary transport proteins. Proteins that in some way facilitate transport across one or more biological membranes but do not themselves participate directly in transport are included in this class. These proteins always function in conjunction with one or more established transport systems. They may provide a function connected with energy coupling to transport, play a structural role in complex formation, serve a biogenic or stability function or function in regulation.
View Families
8.A.1 The Membrane Fusion Protein (MFP) Family
8.A.2 The Secretin Auxiliary Lipoprotein (SAL) Family
8.A.3 The Cytoplasmic Membrane-Periplasmic Auxiliary-1 (MPA1) Protein with Cytoplasmic (C) Domain (MPA1-C or MPA1+C) Family
8.A.4 The Cytoplasmic Membrane-Periplasmic Auxiliary-2 (MPA2) Family
8.A.5 The Voltage-gated K+ Channel β-subunit (Kvβ) Family
8.A.6 The Auxiliary Nutrient Transporter (ANT) Family
8.A.7 The Phosphotransferase System Enzyme I (EI) Family
8.A.8 The Phosphotransferase System HPr (HPr) Family
8.A.9 The rBAT Transport Accessory Protein (rBAT) Family
8.A.10 The Slow Voltage-gated K+ Channel Accessory Protein (MinK) Family
8.A.11 The Immunophilin-like Prolyl:peptidyl Isomerase Regulator (I-PPI) Family
8.A.12 The ABC Bacteriocin Exporter Accessory Protein (BEA) Family
8.A.13 The Tetratricopeptide Repeat (Tpr1) Family
8.A.14 The Ca2+-activated K+ Channel Auxiliary Subunit Slowpoke-β (Sloβ) Family
8.A.15 The K+ Channel Accessory Protein (KChAP) Family
8.A.16 The Ca+ Channel Auxiliary Subunit γ1-γ8 (CCAγ) Family
8.A.17 The Na+ Channel Auxiliary Subunit β1-β4 (SCA-β) Family
8.A.18 The Ca2+ Channel Auxiliary Subunit α2δ Types 1-4 (CCA-α2δ) Family
8.A.19 The Sodium Channel Auxiliary Subunit TipE (SCAT) Family
8.A.20 The Plant/Algal/Chlorella Nitrate Transporter Accessory Protein (Nar2.1) Family
8.A.21 The Stomatin/Podocin/Band 7/Nephrosis.2/SPFH (Stomatin) Family
8.A.22 The Ca2+ Channel Auxiliary Subunit β Types 1-4 (CCA-β) Family
8.A.23 The Basigin (Basigin) Family
8.A.24 The Ezrin/Radixin/Moesin-binding Phosphoprotein 50 (EBP50) Family
8.A.25 The Ezrin/Radixin/Moesin (Ezrin) Family
8.A.26 The Caveolin (Caveolin) Family
8.A.27 The CDC50 P-type ATPase Lipid Flippase Subunit (CDC50) Family
8.A.28 The Ankyrin (Ankyrin) Family
8.A.29 The Homer1 (Homer1) Family of Excitation-Contraction Coupling Proteins
8.A.30 The Nedd4-Family Interacting Protein-2 (Nedd4) Family
8.A.31 The Ly-6 Neurotoxin-like Protein1 Precursor (Lynx1) Family
8.A.32 The β-Amyloid Cleaving Enzyme (BACE1) Family
8.A.33 The Fatty Acid Binding Protein (FABP) Family
8.A.34 The Endophilin (Endophilin) Family
8.A.35 The Mycobacterial Membrane Protein Small (MmpS) Family
8.A.36 The Trp-3 (SPE-41) Interaction Protein (SPE-38) Family
8.A.37 The Hepcidin (Hepcidin) Family
8.A.38 The Animal Macoilin Regulator of Ion Channels (Macoilin) Family
8.A.39 The Homeobox; Penetratin (Penetratin) Family
8.A.40 The Tetraspanin (Tetraspanin) Family
8.A.41 The Stretch-activated Calcium Channel Auxiliary Protein, Mid1 (Mid1) Family
8.A.42 The small hydrophilic YodL domain/protein (YodL) Family
8.A.43 The NEAT-domain containing methaemoglobin heme sequestration (N-MHS) Family
8.A.44 The Mitochondrial EF Hand Ca2+ Uniporter Regulator (MICU) Family
8.A.45 The Essential MCU Regulator EMRE (EMRE) Family
8.A.46 The Glycan-binding Protein (SusD) Family
8.A.47 The Neuropilin and Tolloid-like (Neto) Family
8.A.48 The Putative Auxiliary Aromatic Acid Exporter (AaeX) Family
8.A.49 The Klotho Auxiliary Protein (Klotho) Family
8.A.50 The AcrZ RND auxiliary subunit (AcrZ) Family
8.A.51 The Dipeptidyl-aminopeptidase-like Protein 6 beta subunit of Kv4 channels (DPP6) Family
8.A.52 The Ubiquitin-related Protein Degradation (UPD) Family
8.A.53 The CLC-K Accessory Subunit, Barttin, (Barttin) Family
8.A.54 The Integrin (Integrin) Family
8.A.55 The IZUMO Sperm-Egg Fusion Protein 1 (IZUMO1) Family
8.A.56 The Wntless Protein (Wls) Family
8.A.57 The Wolfram Syndrome or Wolframin (Wolframin) Family
8.A.58 The Dispanin (Dispanin) Family
8.A.59 The SLC and TCST-Associated Component (STAC-A) Family
8.A.60 The Transmembrane protein 139 (TMEM139) Family
8.A.61 The Endoplasmic Reticulum-derived Vesicle Protein, Erv14 (Erv14) Family
8.A.62 The Transmembrane and Ubiquitin-like domain-containing Protein 1 (Tmub1) Family
8.A.63 The Sigma Non-opioid Intracellular Receptor (S1R) Family
8.A.64 The Phosphoinositide-interacting Protein (PIRT) Family
8.A.65 The Endoplasmic Reticulum (ER)-Plasma Membrane (PM) Junctional Competence Regulator (TMEM110) Family
8.A.66 The Dystrophin (Dystrophin) Family
8.A.67 The Os-9 Quality Control (ERAD) Protein (Os-9) Family
8.A.68 The Endomembrane protein-70 (EMP70) Family
8.A.69 The Pro-apoptotic Bcl-2-Family Protein Bim (Bim) Family
8.A.70 The Endomembrane Morphogenesis TMEM170A (TMEM170A) Family
8.A.71 The RIC3 Protein (RIC3) Family
8.A.72 The Immune Evasion Protein, ICP47 (ICP47) Family
8.A.73 The Mitochondrial ATP synthase Stress-responsive Protein (MASP) Family
8.A.74 The TM9 or Phg1 Targeting Receptor (Phg1) Family
8.A.75 The Transmembrane 4 L6 (TM4L6) Family
8.A.76 The TMEM60/185A/203 or PF14967 (TMEM60/185A/203) Family
8.A.77 The Sheddase (Sheddase) Family
8.A.78 The Insulin Secretion-regulating Lipid Transporter TMEM24 (TMEM24) Family
8.A.79 The 3 TMS cyd Operon Protein, CydX (CydX) Family
8.A.80 The (Pro)Renin Receptor (PRR) Family
8.A.81 The S100 Calcium-binding protein (S100) Family
8.A.82 The Calmodulin Calcium Binding Protein (Calmodulin) Family
8.A.83 The Shisa6 Regulator of Short-term Neuronal Synaptic Plasticity (Shisa) Family
8.A.84 The Insulin Secretion Regulator TMEM59 (TMEM59) Family
8.A.85 The Guanylate Cyclase (GC) Family
8.A.86 The Chloroplast Trigalactosyldiacylglycerol-5 (TGD5) Family.
8.A.87 The TBC1 Domain (TBC1) Family
8.A.88 The calciquestrin (CASQ) Family
8.A.90 The Uroplakin 2/3 (UPK2/3) Family
8.A.91 The Syntaxin (Syntaxin) Family
8.A.92 The G-Protein αβγ Complex (GPC) Family
8.A.93 The Sigma2 Receptor or TMEM97 (S2R) Family
8.A.94 The Adiponectin (Adiponectin) Family
8.A.95 The Transmembrane and TPR Repeat-containing Protein 3 (TMTC3) Family
8.A.96 The TMEM70 (TMEM70) Family
8.A.97 The EPG-3/VMP1 (EPG/VPM) Scramblase Family
8.A.98 The 14-3-3 protein (14-3-3) Family
8.A.99 The BLP Braun's Lipoprotein (Lpp) Family
8.A.101 The TMEM263 (TMEM263) Family
8.A.102 The Reticulon (Reticulon) Family
8.A.103 The Secretory Carrier-Associated Membrane Protein (SCAMP) Family
8.A.104 The 5'-AMP-activated protein kinase (AMPK) Family
8.A.105 The Multi-Copper-containing Ferroxidase (MCFO) Family
8.A.106 The Caltrin/Peptide YY (Caltrin) Family
8.A.107 The V-type ATPase assembly factor, ATP6AP1 (ATP6AP1) Family
8.A.108 The Curvature-stabilizing Protein YOP1 (YOP1) Family
8.A.109 The Endoplasmic Reticulum Junction-forming protein (Lunapark) Family
8.A.110 The Junctophilin (JP) Family
8.A.111 The Store-operated Ca2+ Entry-associated Regulatory Factor (SARAF) Family
8.A.112 The Respiratory Supercomplex Factor (Rcf) Family
8.A.113 The Tentonin or TMEM150 (TMEM150) Family
8.A.114 The Huntington-interacting Protein 14 (HIP14) Family
8.A.115 The Transmembrane Protein 223 (TMEM223) Family
8.A.116 The Transmembrane Inner Ear (TMIE) Family
8.A.117 The Neuroligin (Nlg) Family
8.A.118 The Na+K+-ATPase Beta-Subunit Interacting NKAIN (NKAIN) Family
8.A.119 The Potassium Channel Regulatory Protein Sup-10 (Sup-10) Family
8.A.120 The Mitochondrial StAR-related Lipid Transfer Protein (StAR) Family
8.A.121 The Transmembrane Protein 237 (TMEM237) Family
8.A.122 The Vesicular Membrane Neurensin/TMEM74 (Neurensin/TMEM74) Family
8.A.123 The Cytokine Expression and Secretion Mediator and V-type ATPase regulator, TMEM9 (TMEM9) Family
8.A.124 The Tetra Spanning Protein 1 (Tts1) Family
8.A.125 The Cleft Lip and Palate Transmembrane Protein 1 (Clptm1) Family
8.A.126 The Nuclear Receptor Coactivator 7 (NCOA7) Family
8.A.127 The Receptor Activity-Modifying Protein (RAMP) Family
8.A.128 The Signaling Adaptor Protein KARAP/DAP12/TYROBP (SAP-KDT) Family
8.A.129 The Blood Vessel Epicardial Substance (BVES) Family
8.A.130 The Transmembrane Protein 204 (TMEM204) Family
8.A.131 The Transmembrane Protease Serine 3 (TMPRSS3) Family
8.A.132 The Interferon/Interleukin Receptor (IIR) Family
8.A.133 The SIAH1 E3 ubiquitin-protein ligase (SIAH1) Family
8.A.134 The Vezatin (Vezatin) Family
8.A.135 The Trp Cation Channel Auxiliary Subunit, InaF (InaF) Family
8.A.136 The Alpha/Beta-Arrestin (ARRB) Family
8.A.137 The Clathrin (Clathrin) Family
8.A.138 The Constitutive Expresser of Pathogenesis-related 5 (CPR5) Family
8.A.139 The Angiotensin-converting Enzyme 2 (ACE2) Family
8.A.140 The Lymphoid-restricted Membrane Protein (LRMP) Family
8.A.141 The Eros Chaperone Protein (Eros) Family
8.A.142 The PAT Intramembrane Chaperone Complex (PAT) Family
8.A.143 The TMEM132 (TMEM132) Family
8.A.144 The Nicalin (Nicalin) Family
8.A.145 The TMEM147 (TMEM147) Family
8.A.146 The Nodal Modulator (NOMO) Family
8.A.147 The Peroxiredoxin Heme-binding Protein, Tpx1 (Tpx1) Family
8.A.148 The Plasma Membrane Organizing Center, Eisosome (Eisosome) Family
8.A.149 The Cytoskeleton-associated Protein 4 (CKAP4) Family
8.A.150 The Mitochondrial Metalloendopeptidase OMA1 (OMA1) Family
8.A.151 The IP₃R binding protein released with inositol 1,4,5-trisphosphate (IRBIT) Family
8.A.152 The Interleukin Receptor (ILR) Family
8.A.153 The Regulator of the Flagellar Protein Export Apparatus, FliK (FliK) Family.
8.A.154 The Retinoschisin (RS1) Family
8.A.155 The Curt Protein (CurtP) Family
8.A.156 The MICOS Complex (MICOS-C) Family
8.A.157 The Optineurin (OPTN) Family
8.A.159 The MARCH Ubiquitin Ligase (MARCH) Family
8.A.160 The Catenin (Catenin) Family
8.A.161 The Acyl Protein Thioesterase (APTE) Family
8.A.162 The Cereblon (CRBN) Family
8.A.163 The HSP90/CDC37 (HSP90/CDC37) Family
8.A.164 The Integral Membrane Carbonic Anhydrase XI (CA9) Family
8.A.165 The Calnexin (Calnexin) Family
8.A.166 The Mitochondrial Fission Factor (MFF) Family
8.A.167 The Mitoguardin (MIGA) Family
8.A.168 The Glycophorin (GPh) Family
8.A.169 The Fungal Inheritance of Cortical ER protein 2 (ICE2) Family
8.A.170 The B9-Domain Protein Complex Diffusion Barrier for Ciliary Membrane Proteins (CB9DB) Family
8.A.171 The Transmembrane Protein 168 (TMEM168) Family
8.A.172 The α-Crystallin Chaperone (CryA) Family
8.A.173 The Tubulin (Tubulin) Family
8.A.174 The Cytochrome c Oxidase COX15 Assembly Protein (COX15) Family
8.A.175 The Vasculature Complexity and Connectivity (VCC) Family
8.A.176 The Gephyrin (GPHN) Family
8.A.177 The Tumor Necrosis Factor Ligand Member 6 (TNFL6) Family
8.A.178 The Lipase Atg15 (Atg15) Family
8.A.179 The Novel Acetylcholine Receptor Chaperone (NACHO) Family
8.A.180 The Retinol-binding protein (RBP) Family
8.A.181 The TMEM242 Protein Complex Assembly Factor (TMEM242) Family
8.A.182 The Mitochondrial Cytochrome c Oxidase Assembly Protein, COX20 (COX20) Family
8.A.183 The RelA-associated Inhibitor (RAI) Family
8.A.184 The TransMembrane Protein Tmem160 (Tmem160) Family
8.A.185 The Mitolamban (Mtlbn) Family
8.A.186 The Stereocilin, STRC, Protein (STRC) Family
8.A.187 The Podocalyxin (PODXL) Family
8.A.188 The Rictor/mTORC2 (Rictor) Family
8.A.189 The AP-4 Complex Accessory Subunit RUSC2 (RUSC2) Family
8.A.190 The Allergen Asp F2-like Protein (Asp F2) Family
8.A.191 The Translocon-associated Protein Subunit beta (TPS-Beta) Family
8.A.192 The DnaJ Homolog (DnaJ) Family
8.A.193 The Phosphate Transporter Regulator Tmem174 (Tmem174) Family
8.A.194 The Sorting Nexin (SNX) Family
8.A.195 The Erlin1/2 Complex (Erlin) Family
8.A.196 The Tapasin (Tapasin) Family
8.A.197 The Ephrin (Ephrin) Family
8.A.198 The Salmonella Transmembrane Effector of the SPI-2 Type III Secretion System, SteD, (SteD) Family
8.A.199 The Sarcolamban (Sarcolamban) Family
8.A.200 The LMxysn (LMxysn) Family
8.A.201 The PacL1 Chaparone Protein (PacL1) Family
8.A.202 The Proline-rich Receptor (PrR) Family
8.A.203 The Adaptor Protein 4 Chaparone (AAGAB) Family
8.A.204 The Cadhesin (CDH) Family
8.A.205 The Tmem65 (Tmem65) Family
8.A.206 The Zip8 Regulator 1 (Zip8R1) Family
8.A.207 The Zip8 Regulator 2 (Zip8R2) Family
8.A.208 The Lysosomal Enzyme Trafficking Factor (LYSET) Family
8.A.209 The TMEM214 Glucose Transporter Regulator (TMEM214) Family
8.A.210 The Plasma Membrane Repair (PMR) Family
8.A.211 The PP2C.D Phosphatase SAL1 (SAL1) Family
8.A.212 The d-Amino Acid Peptidase (dAAP) Family
8.A.213 The Bon Domain-containing Protein (Bon DP) Family
8.A.214 Cation Channel Sperm-associated Auxiliary Subunit, TMEM249, (TMEM249) Family
8.A.215 The Plasmalemma Vesicle-associated Protein (PLVAP) Family
8.A.216 The Golgi SNAP Receptor Complex, Member 1 (GOSR1) Family
8.A.217 The Apoptosis Cell Death Regulator (ACDR) Family
8.A.218 The Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Family
8.A.219 The Proline-rich Anti-Microbial Peptide (PrAMP) Family
8.A.220 The n-type Redox-active Conjugated Oligoelectrolyte (RaCOE) Family
8.A.221 The Very Long Chain Fatty Acid Elongase (VLCFA-E) Family
8.A.222 The Huntingtin (HTT) Family
8.A.223 The Translocated Intimin Receptor (TIR) Family
8.A.224 The Splicing factor, Arginine/Serine-rich 19 (SCAF1) Family
8.A.225 The Vacuolar Protein Sorting-associated Protein (VPS) Family
8.A.226 The Dusky-like (Dyl) Family
8.A.227 The Transmembrane Protein 79 (TMEM79) Family
8.A.228 The Collapsin Response Mediator Protein 2 (CRMP2) Family
8.A.229 The Chlamydial Inclusion Membrane Protein, MrcA (MrcA) Family
8.A.230 The Tmem72 (Tmem72) Family
8.A.231 The Quiver/Sleepless//Dreammist (QSD) Family
8.A.232 The Phospholipase A (PlaA)/Accesory Protein (PlaS) (PlaAS) Family
8.A.233 The Scotin (Shisa-5) Family
8.A.234 The Modifier of Hyperactive ACD6 (MHA1) Family
8.A.235 The Chaparone Protein, Xport-A (Xprot-A) Family
8.A.236 The Sugarcane Mosaic Virus 6K2 Protein (ScMV-6K2) Family
8.A.237 The Tumor-associated Calcium Signal Transducer 2 (TACSTD2) Family
8.A.238 The Cell Permeabiity Peptide (CPP) Family
8.A.239 The Cox19 Assembly Protein (Cox19) Family
8.A.240 The Metastasis-associated in Colon Cancer protein 1 (MACC1) Family
8.A.241 The Hypoxia-Inducible Factor-1α (HIF) Family
8.A.242 The NAADP-binding Protein (JPT2) Family
8.A.243 The NPPDP-binding Protein, LSM12 (LSM12) Family
8.A.244 The PROTON ATPase TRANSLOCATION CONTROL 1 (PATROL1 ) Family
8.A.245 The Vascular Endothelial Growth Factor (VEGF) Family
8.A.246 The Peroxisome Proliferator-activated Receptor Gamma Coactivator 1-beta (PGC-1a) Family
8.A.247 The Iron-Regulated Secreted Exoprotein (IrsA) Family
8.A.248 The Ras-related Rab GTPase (RrRG) Family
8.A.249 The 26 S Proteosome (26SP) Family
8.A.250 The Tubby-related Protein 3 (TULP3) Family
8.A.251 The Septin (Septin) Family
8.A.252 The Heme Oxidase (HO) Family
8.A.253 The TMEM45A (TMEM45A) Family
8.A.254 The MrdA/MrdB Complex for Synthesis and Positioning of Peptidoglycan (MrdAB) Family
8.A.255 The Mitochondria-Targeting Organic Sensitizer (MTOS) Family