TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
8.A.1.1.1









Membrane Fusion Protein, EmrA, that function with MFS multidrug exporter, EmrB (Nishino and Yamaguchi 2001).

Bacteria
Proteobacteria
EmrA of E. coli
8.A.1.1.2









The MFP cluster 1 protein, FarA (efflux of antimicrobial long chain fatty acids (Lee et al., 2006); functions with MFS carrier, FarB (TC# 2.A.1.3.20))
Bacteria
Proteobacteria
FarA of Neisseria gonorrhoeae (Q9RQ30)
8.A.1.1.3









MdtN; acts with MdtO (TC# 2.A.85.6.1) and MdtP (TC# 1.B.17.3.9) (Sulavik et al., 2001).

Bacteria
Proteobacteria
MdtN of E. coli (B1LPP9)
8.A.1.1.4









Membrane fusion protein, YiaV

Bacteria
Proteobacteria
YiaV of E. coli
8.A.1.2.1









CzcB of MFP cluster 2 (functions with RND porter CzcA, TC# 1.A.6.1.2 and CzcC, TC# 1.B.17.2.1).

Bacteria
Proteobacteria
CzcB of Alcaligenes eutrophus
8.A.1.2.2









Uncharacterized MFP of 314aas and 1 TMS.

Bacteria
Proteobacteria
MFP of Bdellovibrio exovorus
8.A.1.3.1









MFP cluster 3 (function with ABC porters) (Pimenta et al., 2005)
Bacteria
Proteobacteria
HlyD of E. coli
8.A.1.3.2









MFP (cluster3). CyaD (functions with CyaB (TC# 3.A.1.109.2)) (Glaser et al., 1988)
Bacteria
Proteobacteria
CyaD of Bordetella pertussis (P11091)
8.A.1.3.3









The MFP, EexE of cluster 3 (functions with the ABC porter EexD, (TC# 3.A.1.110.10) and OMF EexF (TC# 1.b.17.1.3)) (Gimmestad et al., 2006

).

Bacteria
Proteobacteria
EexE of Azotobacter vinelandii (C1DS85)
8.A.1.3.4









Leukotoxin export MFP protein of 457 aas, TdcA (Guthmiller et al. 1995).  Functions with the ABC exporter, LtxB (TC# 3.A.109.8) and the TolC-like OMF protein, TdeA (TC# 1.B.17.3.11).

Bacteria
Proteobacteria
Leukotoxin export MFP of Aggregatibacter (Actinobacillus; Haemophilus) actinomycetemcomitans
8.A.1.3.5









Uncharacterized MFP of 346 aas and 1 N-terminal TMS. Possibly functions with an RND pump.

Bacteria
Proteobacteria
UP of Parvularcula oceani
8.A.1.4.1









Mesenterecin Y105 (bacteriocin) secresion accessory protein, MesE  of 457 aas (cluster 4). Functions with MesD; TC#3.A.1.112.8.

Bacteria
Firmicutes
MesE of Leuconostoc mesenteroides
8.A.1.4.2









Competence factor transport accessory protein, ComB
Bacteria
Firmicutes
ComB of Streptococcus pneumoniae
8.A.1.5.1









Open reading frame, Orf2
Bacteria
Firmicutes
Orf2 of Lactobacillus gasseri
8.A.1.6.1









Acridine efflux pump constituent, AcrA
Bacteria
Proteobacteria
AcrA of E. coli (P0AE06)
8.A.1.6.2









The multidrug efflux pump constituent, MdtA [may form a complex with MdtB and MdtC (2.A.6.2.12), both RND proteins. All three proteins appear to be required for resistance (Baranova and Nikaido, 2002).

Bacteria
Proteobacteria
MdtA of E. coli (P76397)
8.A.1.6.3









Multidrug resistance protein MdtE (YhiU).  Functions with MdtF (TC# 8.A.1.6.3).

Bacteria
Proteobacteria
MdtE of E. coli
8.A.1.6.4









Cation translocating membrane fusion protein of 295 aas

Bacteria
Planctomycetes
MFP of Rhodopirellula baltica
8.A.1.7.1









MFP, AaeA, that functions with AaeB, a γ-hydroxybenzoate efflux pump, a member of the Aromatic Acid Exporter Family (TC# 2.A.85) (Van Dyk et al., 2004). Several aromatic carboxylic acids serve as inducers of yhcRQP operon expression.

Bacteria
Proteobacteria
AaeA of Escherichia coli (P46482)