8.A.119. The Potassium Channel Regulatory Protein Sup-10 (Sup-10) Family
The proteins within this family seem to have multiple functions. One of these is to coordinate muscle contraction as a regulatory subunit of nonessential potassium channel complexes such as the Sup-9 K+ channel of C. elegans (TC# 1.A.1.9.7). It also forms a complex with MFS protein Unc-93 which may also play a regulatory role in this complex (de la Cruz et al. 2003).
This family belongs to the: Vesicle-associated Membrane Protein (VAMP) Superfamily.
References associated with 8.A.119 family:
de la Cruz, I.P., J.Z. Levin, C. Cummins, P. Anderson, and H.R. Horvitz. (2003). sup-9, sup-10, and unc-93 may encode components of a two-pore K+ channel that coordinates muscle contraction in Caenorhabditis elegans. J. Neurosci. 23: 9133-9145. 14534247