TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
8.A.227.1.1









The TMEM79 protein in humans, Matt, is of 394 aas with a 200 aa long N-terminal domain followed by a C-terminal integral membrane domain with 5 putative TMSs. It regulates TRPV3 (TC# 1.A.4.2.9) (Lei et al. 2023) and contributes to epidermal integrity and the skin barrier function. It also plays roles in the lamellar granule (LG) secretory system and in stratum corneum (SC) epithelial cell formation. It is involvement of skin TRPV3 temperature detection regulation in mice (Lei et al. 2023).

Eukaryota
Metazoa, Chordata
TMEM79 of Homo sapiens
8.A.227.1.2









Uncharacterized protein of 536 aas and 7 C-terminal TMSs.  The N-terminal 290 aas and hydrophilic while the remainder of the protein is hydrophobic with 7 putative TMSs.

Eukaryota
Heterolobosea
UP of Naegleria gruberi
8.A.227.1.3









MAPEG family protein of 171 aas and 5 TMSs in a 2 + 3 TMS arrangement.

Bacteria
Pseudomonadota
MAPEG protein of Bradyrhizobium sp.
8.A.227.1.4









Uncharacterized protein of 385 aas and 7 - 9 TMSs in a 2 + 2 + 3 TMS arrangement with possibly 2 more TMSs in a 3 + 2 + 4 TMS arrangement.

Eukaryota
Metazoa, Mollusca
UP of Mytilus edulis
8.A.227.1.5









TMEM79 of 187 aas and 5 TMSs in a 2 + 3 TMS arrangement.

Eukaryota
Metazoa, Echinodermata
TMEM79 of Holothuria leucospilota
8.A.227.1.6









Epithelial cell maturation (EMC) protein of 448 aas and 5 (or 7) TMSs in a 3 + 2 (+- 2) TMS arrangement.

Eukaryota
Metazoa, Arthropoda
EMC protein of Tyrophagus putrescentiae
8.A.227.1.7









C-myc promoter-binding protein of 206 aas and 5 TMSs in a 2 + 3 TMS arrangement.

Eukaryota
Metazoa, Mollusca
C-myc BP of Plakobranchus ocellatus
8.A.227.1.8









Eomesodermin-like protein of 932 aas with 5 C-terminal TMSs in a 2 + 3 TMS arrangement.

Eukaryota
Metazoa, Mollusca
ELP of Biomphalaria glabrata