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8.A.23.1.2 Extracellular chaperone protein precursor, Embigin. Interacts with MCT2 (2.A.1.13.5) (Ovens et al., 2010; Halestrap 2012). Embigin facilitates monocarboxylate transporter 1 localization to the plasma membrane and its transition to a decoupling state (Xu et al. 2022).
Accession Number:	Q6PCB8
Protein Name:	Embigin
Length:	327
Molecular Weight:	36881.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	1
Location¹ / Topology² / Orientation³:	Membrane¹ / Single-pass type I membrane protein²
Substrate

Entrez Gene ID:	133418
Pfam:	PF07679
KEGG:	hsa:133418
Gene Ontology GO:0016021 C:integral to membrane
References (3) [1] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [3] “Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.” Wollscheid B.et.al. 19349973

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MRALPGLLEA RARTPRLLLL QCLLAAARPS SADGSAPDSP FTSPPLREEI MANNFSLESH 
61:	NISLTEHSSM PVEKNITLER PSNVNLTCQF TTSGDLNAVN VTWKKDGEQL ENNYLVSATG 
121:	STLYTQYRFT IINSKQMGSY SCFFREEKEQ RGTFNFKVPE LHGKNKPLIS YVGDSTVLTC 
181:	KCQNCFPLNW TWYSSNGSVK VPVGVQMNKY VINGTYANET KLKITQLLEE DGESYWCRAL 
241:	FQLGESEEHI ELVVLSYLVP LKPFLVIVAE VILLVATILL CEKYTQKKKK HSDEGKEFEQ 
301:	IEQLKSDDSN GIENNVPRHR KNESLGQ

8.A.23.1.2
Extracellular chaperone protein precursor, Embigin. Interacts with MCT2 (2.A.1.13.5) (Ovens et al., 2010; Halestrap 2012). Embigin facilitates monocarboxylate transporter 1 localization to the plasma membrane and its transition to a decoupling state (Xu et al. 2022).

Cross database links:

Gene Ontology

References (3)

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8.A.23.1.2Extracellular chaperone protein precursor, Embigin. Interacts with MCT2 (2.A.1.13.5) (Ovens et al., 2010; Halestrap 2012). Embigin facilitates monocarboxylate transporter 1 localization to the plasma membrane and its transition to a decoupling state (Xu et al. 2022).

Cross database links:

Gene Ontology

References (3)

External Searches:

Analyze:

8.A.23.1.2
Extracellular chaperone protein precursor, Embigin. Interacts with MCT2 (2.A.1.13.5) (Ovens et al., 2010; Halestrap 2012). Embigin facilitates monocarboxylate transporter 1 localization to the plasma membrane and its transition to a decoupling state (Xu et al. 2022).