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| Accession Number: | P16573 |
| Protein Name: | ECTO aka C-BAT aka GP110 |
| Length: | 519 |
| Molecular Weight: | 57264.00 |
| Species: | Rattus norvegicus (Rat) [10116] |
| Number of TMSs: | 1 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Single-pass type I membrane protein2 |
| Substrate | |
Cross database links:
| RefSeq: | NP_001029032.1 NP_001029033.1 NP_001029034.1 NP_113943.1 |
|---|---|
| Entrez Gene ID: | 81613 |
| Pfam: | PF00047 PF07686 |
| KEGG: | rno:81613 |
Gene Ontology
GO:0005887
C:integral to plasma membrane
GO:0005515
F:protein binding
GO:0007155
P:cell adhesion
GO:0043406
P:positive regulation of MAP kinase activity
GO:0007165
P:signal transduction
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References (10)[1] “Cloning and expression of a cDNA coding for a rat liver plasma membrane ecto-ATPase. The primary structure of the ecto-ATPase is similar to that of the human biliary glycoprotein I.” Lin S.-H.et.al. 2527235 [2] “Different isoforms and stock-specific variants of the cell adhesion molecule C-CAM (cell-CAM 105) in rat liver.” Edlund M.et.al. 8504806 [3] “Molecular cloning and expression of a new rat liver cell-CAM105 isoform. Differential phosphorylation of isoforms.” Culic O.et.al. 1637321 [4] “The cytoplasmic domain of C-CAM is required for C-CAM-mediated adhesion function: studies of a C-CAM transcript containing an unspliced intron.” Cheung P.H.et.al. 8240240 [5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [6] “The cell adhesion molecule Cell-CAM 105 is an ecto-ATPase and a member of the immunoglobulin superfamily.” Aurivillius M.et.al. 2141577 [7] “Characterisation of the ATP-dependent taurocholate-carrier protein (gp110) of the hepatocyte canalicular membrane.” Becker A.et.al. 8513803 [8] “The rat liver ecto-ATPase is also a canalicular bile acid transport protein.” Sippel C.J.et.al. 8420979 [9] “pp120/ecto-ATPase, an endogenous substrate of the insulin receptor tyrosine kinase, is expressed as two variably spliced isoforms.” Najjae S.M.et.al. 8380406 [10] “Immunochemical characterization of two isoforms of rat liver ecto-ATPase that show an immunological and structural identity with a glycoprotein cell-adhesion molecule with Mr 105,000.” Lin S.-H.et.al. 1831973
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MELASARLLR GQIPWRGLLL TASLLTYWSP LTTAQVTVDA VPPNVVEESS VLLLTHNLPQ 61: EFQVFYWYKV TTTGLNSEIA RYIRSSNTSQ TEPAYSGRVT IYSNGSLFFQ NVNKTDEGPY 121: TLSVIDKQFN PIQTSVQFRV YPALQKPNVT GNNSNPMEGE PFVSLMCEPY TNNTSYLWSR 181: NGESLSEGDR VTFSEGNRTL TLLNVRRTDK GYYECEARNP ATFNRSDPFN LDVIYGPDAP 241: VISPPDIYLH QGSNLNLSCH ADSNPPAQYF WLINEKLQTS SQELFISNIT TNNSGTYACF 301: VNNTVTGLSR TTVKNITVFE PVTQPSIQIT NTTVKELGSV TLTCFSKDTG VSVRWLFNSQ 361: SLQLTDRMTL SQDNSTLRID PIKREDAGDY QCEISNPVSF RISHPIKLDV IPDPTQGNSG 421: LSEGAIAGIV IGSVAGVALI AALAYFLYSR KTGGGSDHRD LTEHKPSTSS HNLGPSDDSP 481: NKVDDVSYSV LNFNAQQSKR PTSASSSPTE TVYSVVKKK