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8.A.23.1.42 Dual leucine zipper kinase, Dlk, or mitogen-activated protein kinase kinase kinase 12, MAP3K12, of 859 aas and possibly two adjacent TMSs. It is part of a non-canonical MAPK signaling pathway (Huang et al. 2017).
Accession Number:	Q12852
Protein Name:	Mitogen-activated protein kinase kinase kinase 12
Length:	859
Molecular Weight:	93219.00
Species:	Homo sapiens (Human) [9606]
Number of TMSs:	2
Location¹ / Topology² / Orientation³:	Cytoplasm¹
Substrate	protein

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

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FASTA formatted sequence

1:	MACLHETRTP SPSFGGFVST LSEASMRKLD PDTSDCTPEK DLTPTHVLQL HEQDAGGPGG 
61:	AAGSPESRAS RVRADEVRLQ CQSGSGFLEG LFGCLRPVWT MIGKAYSTEH KQQQEDLWEV 
121:	PFEEILDLQW VGSGAQGAVF LGRFHGEEVA VKKVRDLKET DIKHLRKLKH PNIITFKGVC 
181:	TQAPCYCILM EFCAQGQLYE VLRAGRPVTP SLLVDWSMGI AGGMNYLHLH KIIHRDLKSP 
241:	NMLITYDDVV KISDFGTSKE LSDKSTKMSF AGTVAWMAPE VIRNEPVSEK VDIWSFGVVL 
301:	WELLTGEIPY KDVDSSAIIW GVGSNSLHLP VPSSCPDGFK ILLRQCWNSK PRNRPSFRQI 
361:	LLHLDIASAD VLSTPQETYF KSQAEWREEV KLHFEKIKSE GTCLHRLEEE LVMRRREELR 
421:	HALDIREHYE RKLERANNLY MELNALMLQL ELKERELLRR EQALERRCPG LLKPHPSRGL 
481:	LHGNTMEKLI KKRNVPQKLS PHSKRPDILK TESLLPKLDA ALSGVGLPGC PKGPPSPGRS 
541:	RRGKTRHRKA SAKGSCGDLP GLRTAVPPHE PGGPGSPGGL GGGPSAWEAC PPALRGLHHD 
601:	LLLRKMSSSS PDLLSAALGS RGRGATGGAG DPGSPPPARG DTPPSEGSAP GSTSPDSPGG 
661:	AKGEPPPPVG PGEGVGLLGT GREGTSGRGG SRAGSQHLTP AALLYRAAVT RSQKRGISSE 
721:	EEEGEVDSEV ELTSSQRWPQ SLNMRQSLST FSSENPSDGE EGTASEPSPS GTPEVGSTNT 
781:	DERPDERSDD MCSQGSEIPL DPPPSEVIPG PEPSSLPIPH QELLRERGPP NSEDSDCDST 
841:	ELDNSNSVDA LRPPASLPP

8.A.23.1.42
Dual leucine zipper kinase, Dlk, or mitogen-activated protein kinase kinase kinase 12, MAP3K12, of 859 aas and possibly two adjacent TMSs. It is part of a non-canonical MAPK signaling pathway (Huang et al. 2017).

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8.A.23.1.42Dual leucine zipper kinase, Dlk, or mitogen-activated protein kinase kinase kinase 12, MAP3K12, of 859 aas and possibly two adjacent TMSs. It is part of a non-canonical MAPK signaling pathway (Huang et al. 2017).

Cross database links:

External Searches:

Analyze:

8.A.23.1.42
Dual leucine zipper kinase, Dlk, or mitogen-activated protein kinase kinase kinase 12, MAP3K12, of 859 aas and possibly two adjacent TMSs. It is part of a non-canonical MAPK signaling pathway (Huang et al. 2017).