8.A.23.1.5 Hepatocyte cell adhesion molecule (CAM) precursor of 416 aas. Important for interactions, trafficking and function of ClC2 (CLC-2) in several tissues including the nervious system where it influences human leukodystrophies (Capdevila-Nortes et al. 2015).
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Accession Number: | Q14CZ8 |
Protein Name: | Hepatocyte cell adhesion molecule |
Length: | 416 |
Molecular Weight: | 46026.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 1 |
Location1 / Topology2 / Orientation3: |
Cytoplasm1 |
Substrate |
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1: MKRERGALSR ASRALRLAPF VYLLLIQTDP LEGVNITSPV RLIHGTVGKS ALLSVQYSST
61: SSDRPVVKWQ LKRDKPVTVV QSIGTEVIGT LRPDYRDRIR LFENGSLLLS DLQLADEGTY
121: EVEISITDDT FTGEKTINLT VDVPISRPQV LVASTTVLEL SEAFTLNCSH ENGTKPSYTW
181: LKDGKPLLND SRMLLSPDQK VLTITRVLME DDDLYSCMVE NPISQGRSLP VKITVYRRSS
241: LYIILSTGGI FLLVTLVTVC ACWKPSKRKQ KKLEKQNSLE YMDQNDDRLK PEADTLPRSG
301: EQERKNPMAL YILKDKDSPE TEENPAPEPR SATEPGPPGY SVSPAVPGRS PGLPIRSARR
361: YPRSPARSPA TGRTHSSPPR APSSPGRSRS ASRTLRTAGV HIIREQDEAG PVEISA