8.A.23.1.63
Carcinoembryonic antigen-related cell adhesion molecule 6 preproprotein (CEACAM6) is of 344 aas and 1 C-terminal TMS. Non-coding microRNAs (miRNAs) play critical roles in tumor progression and hold promise as therapeutic agents for multiple cancers. MicroRNA 29a (miR-29a) is a tumor suppressor miRNA that inhibits cancer cell growth and tumor progression in non-small cell lung cancer. Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), which plays an important role in lung cancer progression, has been identified as a target of miR-29a. Delivery of miR-29a to lung adenocarcinoma cells has therapeutic potential as a unique cancer treatment approach (Son et al. 2023).
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| Accession Number: | NP_002474.4 |
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| Protein Name: | NP_002474.4 carcinoembryonic antigen-related cell adhesion molecule 6 preproprotein [Homo sapiens] |
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| Length: | 345 |
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| Molecular Weight: | |
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| Species: | Homo sapiens [9606] |
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| Number of TMSs: | 1 |
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| Substrate |
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1: MGPPSAPPCR LHVPWKEVLL TASLLTFWNP PTTAKLTIES TPFNVAEGKE VLLLAHNLPQ
61: NRIGYSWYKG ERVDGNSLIV GYVIGTQQAT PGPAYSGRET IYPNASLLIQ NVTQNDTGFY
121: TLQVIKSDLV NEEATGQFHV YPELPKPSIS SNNSNPVEDK DAVAFTCEPE VQNTTYLWWV
181: NGQSLPVSPR LQLSNGNMTL TLLSVKRNDA GSYECEIQNP ASANRSDPVT LNVLYGPDVP
241: TISPSKANYR PGENLNLSCH AASNPPAQYS WFINGTFQQS TQELFIPNIT VNNSGSYMCQ
301: AHNSATGLNR TTVTMITVSG SAPVLSAVAT VGITIGVLAR VALI