8.A.23.2.1 T-cell surface glycoprotein, CD4, of 458 aas and 2 TMSs, N- and C-terminal. It is the receptor for HIV and other viruses (see family description) (Raphael et al. 2020).
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Accession Number: | P01730 |
Protein Name: | T-cell surface glycoprotein CD4 |
Length: | 458 |
Molecular Weight: | 51111.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 1 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Single-pass type I membrane protein2 |
Substrate |
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1: MNRGVPFRHL LLVLQLALLP AATQGKKVVL GKKGDTVELT CTASQKKSIQ FHWKNSNQIK
61: ILGNQGSFLT KGPSKLNDRA DSRRSLWDQG NFPLIIKNLK IEDSDTYICE VEDQKEEVQL
121: LVFGLTANSD THLLQGQSLT LTLESPPGSS PSVQCRSPRG KNIQGGKTLS VSQLELQDSG
181: TWTCTVLQNQ KKVEFKIDIV VLAFQKASSI VYKKEGEQVE FSFPLAFTVE KLTGSGELWW
241: QAERASSSKS WITFDLKNKE VSVKRVTQDP KLQMGKKLPL HLTLPQALPQ YAGSGNLTLA
301: LEAKTGKLHQ EVNLVVMRAT QLQKNLTCEV WGPTSPKLML SLKLENKEAK VSKREKAVWV
361: LNPEAGMWQC LLSDSGQVLL ESNIKVLPTW STPVQPMALI VLGGVAGLLL FIGLGIFFCV
421: RCRHRRRQAE RMSQIKRLLS EKKTCQCPHR FQKTCSPI