8.A.25.1.2
The 4.1R protein of 864 aas. Interacts with many membrane transporters, adhesins and receptors as well as cytoskelectal proteins to help organize the cell envelope (Baines et al. 2014). For example, it interacts with the PMCA1b ATPase (TC# 3.A.3.2.25) (Diaz de Barboza et al. 2015). It affects photodynamic therapy for B16 melanoma by regulating the transport of 5-aminolevulinic acid (Li et al. 2021).
|
| Accession Number: | P11171 |
|---|
| Protein Name: | Protein 4.1 |
|---|
| Length: | 864 |
|---|
| Molecular Weight: | 97017.00 |
|---|
| Species: | Homo sapiens (Human) [9606] |
|---|
| Location1 / Topology2 / Orientation3: |
Cytoplasm1 |
|---|
| Substrate |
|
|---|
1: MTTEKSLVTE AENSQHQQKE EGEEAINSGQ QEPQQEESCQ TAAEGDNWCE QKLKASNGDT
61: PTHEDLTKNK ERTSESRGLS RLFSSFLKRP KSQVSEEEGK EVESDKEKGE GGQKEIEFGT
121: SLDEEIILKA PIAAPEPELK TDPSLDLHSL SSAETQPAQE ELREDPDFEI KEGEGLEECS
181: KIEVKEESPQ SKAETELKAS QKPIRKHRNM HCKVSLLDDT VYECVVEKHA KGQDLLKRVC
241: EHLNLLEEDY FGLAIWDNAT SKTWLDSAKE IKKQVRGVPW NFTFNVKFYP PDPAQLTEDI
301: TRYYLCLQLR QDIVAGRLPC SFATLALLGS YTIQSELGDY DPELHGVDYV SDFKLAPNQT
361: KELEEKVMEL HKSYRSMTPA QADLEFLENA KKLSMYGVDL HKAKDLEGVD IILGVCSSGL
421: LVYKDKLRIN RFPWPKVLKI SYKRSSFFIK IRPGEQEQYE STIGFKLPSY RAAKKLWKVC
481: VEHHTFFRLT STDTIPKSKF LALGSKFRYS GRTQAQTRQA SALIDRPAPH FERTASKRAS
541: RSLDGAAAVD SADRSPRPTS APAITQGQVA EGGVLDASAK KTVVPKAQKE TVKAEVKKED
601: EPPEQAEPEP TEAWKVEKTH IEVTVPTSNG DQTQKLAEKT EDLIRMRKKK RERLDGENIY
661: IRHSNLMLED LDKSQEEIKK HHASISELKK NFMESVPEPR PSEWDKRLST HSPFRTLNIN
721: GQIPTGEGPP LVKTQTVTIS DNANAVKSEI PTKDVPIVHT ETKTITYEAA QTDDNSGDLD
781: PGVLLTAQTI TSETPSSTTT TQITKTVKGG ISETRIEKRI VITGDADIDH DQVLVQAIKE
841: AKEQHPDMSV TKVVVHQETE IADE