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Accession Number: | Q01469 |
Protein Name: | Fatty acid-binding protein, epidermal aka FABP |
Length: | 135 |
Molecular Weight: | 15164.00 |
Species: | Homo sapiens (Human) [9606] |
Location1 / Topology2 / Orientation3: | Cytoplasm1 |
Substrate |
Cross database links:
RefSeq: | NP_001435.1 |
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Entrez Gene ID: | 2171 |
Pfam: | PF00061 |
OMIM: |
605168 gene |
KEGG: | hsa:2171 |
Gene Ontology
GO:0005737
C:cytoplasm
GO:0005504
F:fatty acid binding
GO:0005515
F:protein binding
GO:0005215
F:transporter activity
GO:0008544
P:epidermis development
GO:0006629
P:lipid metabolic process
GO:0006810
P:transport
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References (11)[1] “Molecular cloning and expression of a novel keratinocyte protein (psoriasis-associated fatty acid-binding protein [PA-FABP]) that is highly up-regulated in psoriatic skin and that shares similarity to fatty acid-binding proteins.” Madsen P.S.et.al. 1512466 [2] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [3] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [4] “Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.” Gevaert K.et.al. 12665801 [5] “Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes.” Rasmussen H.H.et.al. 1286667 [6] “Purification and characterization of the human epidermal fatty acid-binding protein: localization during epidermal cell differentiation in vivo and in vitro.” Siegenthaler G.et.al. 8092987 [7] “Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.” Rush J.et.al. 15592455 [8] “Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.” Gauci S.et.al. 19413330 [9] “Lysine acetylation targets protein complexes and co-regulates major cellular functions.” Choudhary C.et.al. 19608861 [10] “Expression, purification and crystal structure determination of recombinant human epidermal-type fatty acid-binding protein.” Hohoff C.et.al. 10493790 [11] “Solution structure and backbone dynamics of human epidermal-type fatty acid-binding protein (E-FABP).” Gutierrez-Gonzalez L.H.et.al. 12049637
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Structure: | |
External Searches:
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Analyze:
Predict TMSs (Predict number of transmembrane segments) | ||||
FASTA formatted sequence |
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1: MATVQQLEGR WRLVDSKGFD EYMKELGVGI ALRKMGAMAK PDCIITCDGK NLTIKTESTL 61: KTTQFSCTLG EKFEETTADG RKTQTVCNFT DGALVQHQEW DGKESTITRK LKDGKLVVEC 121: VMNNVTCTRI YEKVE