8.A.34.1.3
SH3 and cysteine-rich domain-containing protein 3, STAC3 of 364 aas. Excitation-contraction (EC) coupling in skeletal muscle requires functional and mechanical coupling between L-type voltage-gated calcium channels (CaV1.1) and the ryanodine receptor (RyR1), and STAC3 is an essential protein for EC coupling. It is part of a group of three proteins that can bind and modulate L-type voltage-gated calcium channels (Wong King Yuen et al. 2017).
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| Accession Number: | Q96MF3 |
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| Protein Name: | cDNA FLJ32449 fis, clone SKMUS2001662, moderately similar to Oryctolagus cuniculus CARP mRNA |
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| Length: | 258 |
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| Molecular Weight: | 29111.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Substrate |
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1: MDFISIQQLV SGERVEGKVL GFGHGVPDPG AWPSDWRRGP QEAVAREKLK LEEEKKKKLE
61: RFNSTRFNLD NLADLENLVQ RRKKRLRHRV PPRKPEPLVK PQSQAQVEPV GLEMFLKAAA
121: ENQEYLIDKY LTDGGDPNAH DKLHRTALHW ACLKGHSQLV NKLLVAGATV DARDLLDRTP
181: VFWACRGGHL VILKQLLNQG ARVNARDKIG STPLHVAVRT RHPDCLEHLI ECGAHLNAPS
241: VRFKLHWCRP VLLVGLGP