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8.A.54.1.3
Cochlin of 550 aas and 1 N-terminal TMS, possibly with more TMSs in the rest of the protein.  Shows similarity with a protein of TC# 2.A.74.1.6 as well as 8.A.54.1.1.  binds to ZCTL2 (SLC44A2), a putative choline transporter (TC# 2.A.92.1.2) (Kommareddi et al. 2007). It may be associated with Meniere's Disease (Lopez-Escamez et al. 2018).

Accession Number:O43405
Protein Name:Cochlin
Length:550
Molecular Weight:59483.00
Species:Homo sapiens (Human) [9606]
Location1 / Topology2 / Orientation3: Secreted1
Substrate

Cross database links:

Structure:
1JBI     

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MSAAWIPALG LGVCLLLLPG PAGSEGAAPI AITCFTRGLD IRKEKADVLC PGGCPLEEFS 
61:	VYGNIVYASV SSICGAAVHR GVISNSGGPV RVYSLPGREN YSSVDANGIQ SQMLSRWSAS 
121:	FTVTKGKSST QEATGQAVST AHPPTGKRLK KTPEKKTGNK DCKADIAFLI DGSFNIGQRR 
181:	FNLQKNFVGK VALMLGIGTE GPHVGLVQAS EHPKIEFYLK NFTSAKDVLF AIKEVGFRGG 
241:	NSNTGKALKH TAQKFFTVDA GVRKGIPKVV VVFIDGWPSD DIEEAGIVAR EFGVNVFIVS 
301:	VAKPIPEELG MVQDVTFVDK AVCRNNGFFS YHMPNWFGTT KYVKPLVQKL CTHEQMMCSK 
361:	TCYNSVNIAF LIDGSSSVGD SNFRLMLEFV SNIAKTFEIS DIGAKIAAVQ FTYDQRTEFS 
421:	FTDYSTKENV LAVIRNIRYM SGGTATGDAI SFTVRNVFGP IRESPNKNFL VIVTDGQSYD 
481:	DVQGPAAAAH DAGITIFSVG VAWAPLDDLK DMASKPKESH AFFTREFTGL EPIVSDVIRG 
541:	ICRDFLESQQ