8.A.54.1.3
Cochlin of 550 aas and 1 N-terminal TMS, possibly with more TMSs in the rest of the protein. Shows similarity with a protein of TC# 2.A.74.1.6 as well as 8.A.54.1.1. binds to ZCTL2 (SLC44A2), a putative choline transporter (TC# 2.A.92.1.2) (Kommareddi et al. 2007). It may be associated with Meniere's Disease (Lopez-Escamez et al. 2018).
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| Accession Number: | O43405 |
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| Protein Name: | Cochlin |
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| Length: | 550 |
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| Molecular Weight: | 59483.00 |
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| Species: | Homo sapiens (Human) [9606] |
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| Location1 / Topology2 / Orientation3: |
Secreted1 |
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| Substrate |
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1: MSAAWIPALG LGVCLLLLPG PAGSEGAAPI AITCFTRGLD IRKEKADVLC PGGCPLEEFS
61: VYGNIVYASV SSICGAAVHR GVISNSGGPV RVYSLPGREN YSSVDANGIQ SQMLSRWSAS
121: FTVTKGKSST QEATGQAVST AHPPTGKRLK KTPEKKTGNK DCKADIAFLI DGSFNIGQRR
181: FNLQKNFVGK VALMLGIGTE GPHVGLVQAS EHPKIEFYLK NFTSAKDVLF AIKEVGFRGG
241: NSNTGKALKH TAQKFFTVDA GVRKGIPKVV VVFIDGWPSD DIEEAGIVAR EFGVNVFIVS
301: VAKPIPEELG MVQDVTFVDK AVCRNNGFFS YHMPNWFGTT KYVKPLVQKL CTHEQMMCSK
361: TCYNSVNIAF LIDGSSSVGD SNFRLMLEFV SNIAKTFEIS DIGAKIAAVQ FTYDQRTEFS
421: FTDYSTKENV LAVIRNIRYM SGGTATGDAI SFTVRNVFGP IRESPNKNFL VIVTDGQSYD
481: DVQGPAAAAH DAGITIFSVG VAWAPLDDLK DMASKPKESH AFFTREFTGL EPIVSDVIRG
541: ICRDFLESQQ