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8.A.54.1.7
Integrin alpha-11, α-11, α11, of 1188 aas and 4 TMSs, one N-terminal, two close to each other in a central location in the protein, and one C-terminal. It is a receptor for collagen (Gullberg and Lundgren-Akerlund 2002). Mechanical tension and integrin beta-1 regulate fibroblast functions (Eckes et al. 2006). Cells contain at least two types of collagen receptors: integrins and discoidin domain receptors (DDRs) (Yeh et al. 2012).

Accession Number:Q9UKX5
Protein Name:Integrin alpha-11
Length:1188
Molecular Weight:133470.00
Species:Homo sapiens (Human) [9606]
Number of TMSs:3
Location1 / Topology2 / Orientation3: Membrane1 / Single-pass type I membrane protein2
Substrate

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MDLPRGLVVA WALSLWPGFT DTFNMDTRKP RVIPGSRTAF FGYTVQQHDI SGNKWLVVGA 
61:	PLETNGYQKT GDVYKCPVIH GNCTKLNLGR VTLSNVSERK DNMRLGLSLA TNPKDNSFLA 
121:	CSPLWSHECG SSYYTTGMCS RVNSNFRFSK TVAPALQRCQ TYMDIVIVLD GSNSIYPWVE 
181:	VQHFLINILK KFYIGPGQIQ VGVVQYGEDV VHEFHLNDYR SVKDVVEAAS HIEQRGGTET 
241:	RTAFGIEFAR SEAFQKGGRK GAKKVMIVIT DGESHDSPDL EKVIQQSERD NVTRYAVAVL 
301:	GYYNRRGINP ETFLNEIKYI ASDPDDKHFF NVTDEAALKD IVDALGDRIF SLEGTNKNET 
361:	SFGLEMSQTG FSSHVVEDGV LLGAVGAYDW NGAVLKETSA GKVIPLRESY LKEFPEELKN 
421:	HGAYLGYTVT SVVSSRQGRV YVAGAPRFNH TGKVILFTMH NNRSLTIHQA MRGQQIGSYF 
481:	GSEITSVDID GDGVTDVLLV GAPMYFNEGR ERGKVYVYEL RQNLFVYNGT LKDSHSYQNA 
541:	RFGSSIASVR DLNQDSYNDV VVGAPLEDNH AGAIYIFHGF RGSILKTPKQ RITASELATG 
601:	LQYFGCSIHG QLDLNEDGLI DLAVGALGNA VILWSRPVVQ INASLHFEPS KINIFHRDCK 
661:	RSGRDATCLA AFLCFTPIFL APHFQTTTVG IRYNATMDER RYTPRAHLDE GGDRFTNRAV 
721:	LLSSGQELCE RINFHVLDTA DYVKPVTFSV EYSLEDPDHG PMLDDGWPTT LRVSVPFWNG 
781:	CNEDEHCVPD LVLDARSDLP TAMEYCQRVL RKPAQDCSAY TLSFDTTVFI IESTRQRVAV 
841:	EATLENRGEN AYSTVLNISQ SANLQFASLI QKEDSDGSIE CVNEERRLQK QVCNVSYPFF 
901:	RAKAKVAFRL DFEFSKSIFL HHLEIELAAG SDSNERDSTK EDNVAPLRFH LKYEADVLFT 
961:	RSSSLSHYEV KPNSSLERYD GIGPPFSCIF RIQNLGLFPI HGMMMKITIP IATRSGNRLL 
1021:	KLRDFLTDEA NTSCNIWGNS TEYRPTPVEE DLRRAPQLNH SNSDVVSINC NIRLVPNQEI 
1081:	NFHLLGNLWL RSLKALKYKS MKIMVNAALQ RQFHSPFIFR EEDPSRQIVF EISKQEDWQV 
1141:	PIWIIVGSTL GGLLLLALLV LALWKLGFFR SARRRREPGL DPTPKVLE