TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
8.A.71.1.1









The RIC3 (RIC-3) protein of 369 aas and 2 TMSs.  Promotes functional expression of homomeric alpha-7 and alpha-8 nicotinic acetylcholine receptors at the cell surface (Castelán et al. 2008). Also promote functional expression of homomeric serotoninergic 5-HT3 receptors, and of heteromeric acetylcholine receptors alpha-3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4.7.  Interacts directly with the cytoplasmic domain of the serotonin receptor (TC# 1.A.9.2.3) (Nishtala et al. 2016).

Eukaryota
Metazoa
RIC3 of Homo sapiens
8.A.71.1.2









Ric-3 protein of 505 aas and 2 TMSs

Eukaryota
Metazoa
Ric-3 of Drosophila melanogaster (Fruit fly)
8.A.71.1.3









Ric-3, isoform J of 472 aas and 2 TMSs.

Eukaryota
Metazoa
Ric-3 of Drosophila melanogaster (Fruit fly)
8.A.71.1.4









Ric-3 protein of 394 aas and 2 TMSs.

Eukaryota
Metazoa
Ric-3 of Caenorhabditis vulgaris