8.A.82.2.4 The K+-voltage-gated ion channel interacting protein, KCNIP2 or KCHIP2 protein of 270 aas, a regulator and subunit of K+ channels such as Kv4.3 and Kv1.4 as well as cardiac L-type Ca+ channels (Thomsen et al. 2009; Hovind et al. 2011; Wang et al. 2013). It plays a role in the regulation of ion channel function and stress responses (Hudlikar et al. 2021).
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Accession Number: | Q9NS61 |
Protein Name: | Kv channel-interacting protein 2 |
Length: | 270 |
Molecular Weight: | 30907.00 |
Species: | Homo sapiens (Human) [9606] |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Lipid-anchor2 |
Substrate |
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1: MRGQGRKESL SDSRDLDGSY DQLTGHPPGP TKKALKQRFL KLLPCCGPQA LPSVSETLAA
61: PASLRPHRPR LLDPDSVDDE FELSTVCHRP EGLEQLQEQT KFTRKELQVL YRGFKNECPS
121: GIVNEENFKQ IYSQFFPQGD SSTYATFLFN AFDTNHDGSV SFEDFVAGLS VILRGTVDDR
181: LNWAFNLYDL NKDGCITKEE MLDIMKSIYD MMGKYTYPAL REEAPREHVE SFFQKMDRNK
241: DGVVTIEEFI ESCQKDENIM RSMQLFDNVI