8.A.82.3.1
45 kDa Ca2+-binding protein of 362 aas with an N-terminal TMS, SDF4 or CAB45. Cab45 mediates sorting of a subset of secretory proteins at the trans-Golgi network. In response to Ca2+ influx, Cab45 forms oligomers, enabling it to bind a variety of specific cargo molecules (Blank and von Blume 2017). It has an internal repeat involving residues 47 - 163 and residues 210 - 347.
|
| Accession Number: | Q9BRK5 |
|---|
| Protein Name: | 45 kDa calcium-binding protein |
|---|
| Length: | 362 |
|---|
| Molecular Weight: | 41807.00 |
|---|
| Species: | Homo sapiens (Human) [9606] |
|---|
| Number of TMSs: | 1 |
|---|
| Location1 / Topology2 / Orientation3: |
Cytoplasm1 |
|---|
| Substrate |
|
|---|
1: MVWPWVAMAS RWGPLIGLAP CCLWLLGAVL LMDASARPAN HSSTRERVAN REENEILPPD
61: HLNGVKLEMD GHLNRGFHQE VFLGKDLGGF DEDAEPRRSR RKLMVIFSKV DVNTDRKISA
121: KEMQRWIMEK TAEHFQEAME ESKTHFRAVD PDGDGHVSWD EYKVKFLASK GHSEKEVADA
181: IRLNEELKVD EETQEVLENL KDRWYQADSP PADLLLTEEE FLSFLHPEHS RGMLRFMVKE
241: IVRDLDQDGD KQLSVPEFIS LPVGTVENQQ GQDIDDNWVK DRKKEFEELI DSNHDGIVTA
301: EELESYMDPM NEYNALNEAK QMIAVADENQ NHHLEPEEVL KYSEFFTGSK LVDYARSVHE
361: EF