TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
8.A.94.1.1









Adiponectin of 244 aas and possibly one N-terminal TMS. Description and significance of the human protein can be found in the family description.  Regulates expression of aquaporins, particularly Aqp3, which transports water and glycerol (TC# 1.A.8.9.1 for the rat ortholog) (Tardelli et al. 2017).

Eukaryota
Metazoa, Chordata
Adiponectin of Homo sapiens
8.A.94.1.2









Secreted complement C1q and tumor necrosis factor-related protein 9 of 333 aas and possibly 1 or 2 TMSs. It is a probable adipokine that activates AMPK, AKT, and p44/42 MAPK signaling pathways (Xin et al. 2014). It may have a protective role in cirrhosis progression (Hicks et al. 2017).

Eukaryota
Metazoa, Chordata
C1q or CTRP9 of Homo sapiens
8.A.94.1.3









Complement C1q tumor necrosis factor-related protein 9, CTRP9, of 302 aas and 1 N-terminal TMS. AjCTRP9 is a novel adipokine with pleiotropic functions in immunity and metabolism (Shao et al. 2017).

Eukaryota
Metazoa, Echinodermata
CTRP9 of Apostichopus japonicus
8.A.94.1.4









Complement C1q tumor necrosis factor-related protein 3 isoform X5 of 357 aas and 1 N-terminal TMS.

Eukaryota
Metazoa, Chordata
C1q protein 3 isoform X5 of Papio anubis
8.A.94.1.5









Complement C1q tumor necrosis factor-related protein 1-like of 245 aas and 1 N-terminal TMS.

Eukaryota
Metazoa, Chordata
C1QTNF6A of Nothobranchius furzeri (Turquois hillifish)
8.A.94.1.6









C1QL2 of 287 aas and 1 N-terminal TMS as well as several C-terminal moderate peaks of hydrophobicity that might be TMSs. It may regulate the number of excitatory synapses that are formed on hippocampus neurons but has no effect on inhibitory synapses. May also be a subunit of AMPA receptors (Matthews et al. 2021).

Eukaryota
Metazoa, Chordata
C1QL2 of Homo sapiens