8.B.10.2.1 M-Lycotoxin Hc1a; Lycotoxin I of 25 aas. Forms pores that permeabilize the cell membrane and promotes
efflux of calcium from synaptosomes. It also causes hemolysis and
dissipates voltage gradients across muscle membrane. Potently
inhibits the growth of bacteria, yeast and Leishmania. Is lethal to
lepidopteran larvae. May function both in the prey capture strategy
and in protection from infectious organisms arising from prey
ingestion (Hughes et al. 2008; Adão et al. 2008).
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Accession Number: | P61507 |
Protein Name: | M-lycotoxin-Hc1a |
Length: | 25 |
Molecular Weight: | 2844.00 |
Species: | Hogna carolinensis (Carolina wolf spider) [278031] |
Location1 / Topology2 / Orientation3: |
Secreted1 |
Substrate |
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1: IWLTALKFLG KHAAKHLAKQ QLSKL