Toxin LyeTx 1 of 26 aas. It has antimicrobial activity against the Gram-positive
bacterium, S. aureus (MIC=3.79 µM), the Gram-negative bacterium, E. coli (MIC=7.81 µM) and the yeasts, C. krusei (MIC=26.3 µM) and C. neoformans (MIC=13.2 µM). It also has hemolytic activity against rabbit erythrocytes and forms
pores in lipid bilayers in vitro; pore formation is reduced when
cholesterol is present in the bilayers (Santos et al. 2010). The x-ray structure is known (6CL3_A).
|Protein Name:||Toxin LyeTx 1|
|Species:||Lycosa erythrognatha (Wolf spider)  |
|Location1 / Topology2 / Orientation3:
1: IWLTALKFLG KNLGKHLAKQ QLAKL