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8.B.10.2.3
Toxin LyeTx 1 of 26 aas. It has antimicrobial activity against the Gram-positive bacterium, S. aureus (MIC=3.79 µM), the Gram-negative bacterium, E. coli (MIC=7.81 µM) and the yeasts, C. krusei (MIC=26.3 µM) and C. neoformans (MIC=13.2 µM). It also has hemolytic activity against rabbit erythrocytes and forms pores in lipid bilayers in vitro; pore formation is reduced when cholesterol is present in the bilayers (Santos et al. 2010). The x-ray structure is known (6CL3_A).

Accession Number:C0HJU9
Protein Name:Toxin LyeTx 1
Length:25
Molecular Weight:2834.00
Species:Lycosa erythrognatha (Wolf spider) [332789]
Location1 / Topology2 / Orientation3: Secreted1
Substrate

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Structure:
6CL3     

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FASTA formatted sequence
1:	IWLTALKFLG KNLGKHLAKQ QLAKL