8.B.39.1.1
Conotoxin im23.3 of 70 aas and 1 TMS. It is a neurotoxin that induces excitatory symptoms in mice following intracranial administration (Ye et al. 2012). The 3-d structure of a 42 aa seqence from a similar conotoxin, conotoxin im17.a from the same organism, has been solved (PDB acc# 2LMZ).
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| Accession Number: | D0PX86 |
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| Protein Name: | Conotoxin im23.3 |
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| Length: | 70 |
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| Molecular Weight: | 7825.00 |
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| Species: | Conus imperialis (Imperial cone) [35631] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Secreted1 |
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| Substrate |
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1: MIMRMTLTLF VLVVMTAASA SGDALTEAKR IPYCGQTGAE CYSWCKEQHL IRCCDFVKYV
61: GMNPPADKCR