8.B.6.1.8 Tachystatin-B1 of 42 aas. Exhibits stronger antimicrobial activity against Gram-positive bacteria (S. aureus (IC50 is 7.4 µg/ml)), fungi (C. albicans (IC50 is 3.0 µg/ml) and P. pastoris (IC50 is 0.1 µg/ml)) than Gram-negative bacteria (E.coli, no inhibition at 100 µg/ml). Binds to chitin. Does not cause hemolysis on sheep erythrocytes. Has no blocking activity on the P-type calcium channel.
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Accession Number: | P0C1Z8 |
Protein Name: | Tachystatin-B1 |
Length: | 42 |
Molecular Weight: | 4919.00 |
Species: | Tachypleus tridentatus (Japanese horseshoe crab) [6853] |
Location1 / Topology2 / Orientation3: |
Secreted1 |
Substrate |
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1: YVSCLFRGAR CRVYSGRSCC FGYYCRRDFP GSIFGTCSRR NF