TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
9.A.22.1.1









The NhaE Na+/K+:H+ antiporter.  The gene encoding this protein is adjacent to genes encoding a GntR transcriptional regulator, two ABC ATPases designated NatA1 and NatA2 and an ABC membrane protein designated NatB, all possibly within a single operon.

Bacteria
Firmicutes
NhaE (orf 14) of Bacillus pseudofirmus
9.A.22.1.2









Hypothetical protein.  The encoding gene is adjacent to genes encoding a GntR transcriptional regulator (Q9KDP7), two ABC ATPases (Q9KDP6 and 7) and a putative ABC membrane protein (Q9KDP5), all possibly in a single operon.

Bacteria
Firmicutes
HP of Bacillus halodurans
9.A.22.1.3









Hypothetical protein.  Encoded by a gene adjacent to genes encoding a GntR transcriptional regulator, a similar membrane protein with 6 TMSs in a 2 + 4 arrangement, followed by two genes encoding two ABC ATPases annotated as NatA1 and A2, followed by a membrane protein annotated as NatB2.  These genes may all be in a single operon.

Bacteria
Firmicutes
HP of Bacillus cellulosilyticus
9.A.22.1.4









Uncharacterized protein of 241 aas and 6 TMSs.

Bacteria
Firmicutes
UP of Alkalibacillus haloalkaliphilus
9.A.22.1.5









Uncharacterized protein of 251 aas and 6 TMSs in a 2 + 4 TMS arrangement.

Bacteria
Terrabacteria group
UP of Salilacibacter sp. NKC3-5
9.A.22.1.6









Uncharacterized protein of 243 aas and 6 TMSs in a 2 + 2 + 2 TMS arrangement.

Bacteria
Terrabacteria group
UP of Geomicrobium sp. JCM 19039
9.A.22.1.8









Putative 3-component ABC transporter with two membrane proteins, both of 6 TMSs in a 2 + 4 TMS arrangement and a single ATPase. This system is encoded by 3 genes that are adjacent to each other and a GntR transcription factor gene, and also to a putative Na+ ABC efflux system, NatAB (see 3.A.1.115.4; Cheng et al. 1997).

Bacteria
Terrabacteria group
Putative 3 component ABC transport system with two membrane proteins (E6TQK3 and 4), and one ATPase (E6TQK6), possibly regulated at the GntR-type transcriptional factor (E6TQK5) of Evansella cellulosilytica (Bacillus cellulosilyticus)
9.A.22.2.1









Uncharacterized protein of 243 aas and 6 TMSs.

Bacteria
Firmicutes
UP of Bacillus clausii
9.A.22.2.2









Uncharacterized protein of 240 aas ans 6 TMSs

Bacteria
Terrabacteria group
UP of Alkalihalobacillus lonarensis
9.A.22.3.1









Uncharacterized 6 TMS protein.  Clearly a member of the 9.A.22 family, but also exhibits sequence similarity to the second half (TMSs 7 - 12) of the MFS permease, 2.A.1.62.3.

Bacteria
Firmicutes
UP of Paenibacillus terrae
9.A.22.3.2









Uncharacterized protein of 235 aas and 6 TMSs.

Bacteria
Firmicutes
UP of Thermoactinomyces sp. DSM 45892
9.A.22.3.3









Uncharacterized protein of 249 aas and 6 TMSs.

Bacteria
Firmicutes
UP of Salinibacillus kushneri
9.A.22.3.4









Uncharacterized protein of 229 aas and 6 TMSs.

Bacteria
Terrabacteria group
UP of Thermomicrobiales bacterium (activated sludge metagenome)
9.A.22.3.5









Uncharacterized protein of 241 aas and 6 TMSs

Bacteria
Terrabacteria group
UP of Paenibacillus montaniterrae
9.A.22.3.6









Uncharacterized protein of 248 aas and 6 TMSs in a 2 + 3 + 1 TMS arrangement.

Bacteria
Terrabacteria group
UP of Hazenella coriacea
9.A.22.4.1









Uncharacterized protein of 237 aas and 6 TMSs.

Bacteria
Bacteroidetes
UP of Chryseobacterium gleum
9.A.22.4.2









Uncharacterized protein of 224 aas and 6 TMSs

Bacteria
Proteobacteria
UP of Sphingopyxis sp. MC1
9.A.22.4.3









Uncharacterized protein of 229 aas and 6 TMSs

Bacteria
Proteobacteria
UP of Ensifer adhaerens (Sinorhizobium morelense)  
9.A.22.5.1









Uncharacterized protein of 300 aas and 6 TMSs in a 2 + 2 + 2 TMS arrangement.

Bacteria
Bacteria candidate phyla
UP of Candidatus Peribacter riflensis (groundwater metagenome)
9.A.22.5.2









Uncharacterized protein of 358 aas and 6 TMSs in a 2 + 2 + 2 TMS arrangement.

Bacteria
Bacteria candidate phyla
UP of Candidatus Gracilibacteria bacterium CG2_30_37_12 (groundwater metagenome)
9.A.22.5.3









Uncharacterized protein of 318 aas and 7 or 6 TMSs in a 2 + 2 + 2 or 3 TMS arrangement.

Bacteria
Bacteria candidate phyla
UP of Candidatus Magasanikbacteria bacterium (groundwater metagenome)
9.A.22.5.4









Uncharacterized protein of 343 aas and 7 TMSs in a 2 + 2 + 3 TMS arrangement.

Bacteria
Terrabacteria group
UP of Anaerolineales bacterium (bioreactor metagenome)
9.A.22.5.5









Uncharacterized protein of 349 aas and 7 TMSs in a 1 + 2 + 2 + 2 TMS arrangement.

Bacteria
UP of Microgenomates group bacterium
9.A.22.5.6









Uncharacterized protein of 375 aas and 6 TMSs in a 2 + 2 + 2 TMS arrangement.

Bacteria
Terrabacteria group
UP of Coriobacteriia bacterium (volcano metagenome)
9.A.22.5.7









Uncharacterized protein of 403 aas and 6 TMSs

Bacteria
Terrabacteria group
UP of Hazenella coriacea
9.A.22.5.8









Uncharacterized protein of 452 aas and 6 or 7 TMSs in a 2 + 2 + 2 or 3 TMS arrangement.

Archaea
Euryarchaeota
UP of Haloprofundus marisrubri
9.A.22.5.9









Uncharacterized protein of 397 aas and 6 or 7 TMSs in a 2 + 2 + 2 or 3 TMS arrangement.

Bacteria
Spirochaetes
UP of Leptospiraceae bacterium (activated sludge metagenome)