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9.A.8.1.2
Ferrous iron uptake system

Accession Number:O25396
Protein Name:FeoB aka HP0687
Length:642
Molecular Weight:71423.00
Species:Helicobacter pylori (Campylobacter pylori) [210]
Number of TMSs:9
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate Fe2+

Cross database links:

DIP: DIP-3079N
RefSeq: NP_207481.1   
Entrez Gene ID: 898903   
Pfam: PF07664    PF02421    PF07670   
KEGG: hpy:HP0687   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0005524 F:ATP binding
GO:0015093 F:ferrous iron transmembrane transporter acti...
GO:0005525 F:GTP binding
GO:0015684 P:ferrous iron transport

References (2)

[1] “The complete genome sequence of the gastric pathogen Helicobacter pylori.”  Tomb J.-F.et.al.   9252185
[2] “Iron acquisition and virulence in Helicobacter pylori: a major role for FeoB, a high-affinity ferrous iron transporter.”  Velayudhan J.et.al.   10931324

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence
1:	MKEITIALVG QPNVGKSSLI NALSNAHLKV GNFAGVTVDK MEVGLIHKEH QITIIDLPGT 
61:	YALNDFTTEE KVTKDFLEKG QYDLILNVVD STNLERNLAL SAQLLDTNKK MLLALNMWDE 
121:	AQKEGIKINT EKLSKELGVV CVPTSARSKE DRLNTELLLD EIVRLYSQNT TNNENIKVPS 
181:	QSFKESLKYS QSAQRIAQLV ISENQQNASF EHTYKIDKIL MHKRYGIFIF LGFMFIIFSL 
241:	SFLIGGGVQK ALETGFKFLS DGIKENVANE DLASLVGDGI IGGVGATVSF LPLIVVLYFG 
301:	ISLLETTGYM SRVAFLLDGI LHKFGLHGKS FIPLITGFGC SVPAYMATRT LQNYNERLIT 
361:	LFVIGFMSCS ARLPIYVLFV GSFFPSSSAG FVLFCIYILG AVVALVMAKL LKLSVFKGQT 
421:	ESFIMEMPKY RFPSWRMVYF SIYTKSLSYL KKAGTYILVG AILIWFMSQY PKSDAAMKAY 
481:	KQESLLVNKD TTLSSEAKEE KLKELKTELD KKNLKNSIVG RGGAYLEKVF SPMDFDWRLS 
541:	VSLVTGFMAK EVVVSTLGVL FSLGDQNEKS DAFRGILRKE VSVPSGIAFI VFVMFYIPCF 
601:	AATITFGREA GGIKFVAYLF IFTTVVAYAF SLIAFYATQI LV