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9.B.105.1.3
Undecaprenyl-diphosphatase BcrC (EC 3.6.1.27) (Undecaprenyl pyrophosphate phosphatase)

Accession Number:P94571
Protein Name:Undecaprenyl-diphosphatase BcrC
Length:193
Molecular Weight:21723.00
Species:Bacillus subtilis (strain 168) [224308]
Number of TMSs:5
Location1 / Topology2 / Orientation3: Cell membrane1 / Multi-pass membrane protein2
Substrate Unknown

Cross database links:

Entrez Gene ID: 936946   
Pfam: PF01569   
KEGG: bsu:BSU36530   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0050380 F:undecaprenyl-diphosphatase activity
GO:0007047 P:cellular cell wall organization
GO:0009252 P:peptidoglycan biosynthetic process
GO:0008360 P:regulation of cell shape
GO:0046677 P:response to antibiotic

References (7)

[1] “The Bacillus subtilis genome from gerBC (311 degrees) to licR (334 degrees).”  Presecan E.et.al.   9353933
[2] “The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.”  Kunst F.et.al.   9384377
[3] “Regulation of the Bacillus subtilis bcrC bacitracin resistance gene by two extracytoplasmic function sigma factors.”  Cao M.et.al.   12399481
[4] “YtsCD and YwoA, two independent systems that confer bacitracin resistance to Bacillus subtilis.”  Bernard R.et.al.   14612242
[5] “A bacitracin-resistant Bacillus subtilis gene encodes a homologue of the membrane-spanning subunit of the Bacillus licheniformis ABC transporter.”  Ohki R.et.al.   12486040
[6] “BcrC from Bacillus subtilis acts as an undecaprenyl pyrophosphate phosphatase in bacitracin resistance.”  Bernard R.et.al.   15946938
[7] “Genetic evidence for the actin homolog gene mreBH and the bacitracin resistance gene bcrC as targets of the alternative sigma factor sigI of Bacillus subtilis.”  Tseng C.-L.et.al.   18156261

External Searches:

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MNYEIFKAIH GLSHHNSVLD SIMVFITEYA IVAYALILLA IWLFGNTQSR KHVLYAGITG 
61:	IAGLVINYLI TLVYFEPRPF VAHTVHTLIP HAADASFPSD HTTGALAISI AMLFRNRKIG 
121:	WPLVIFGLLT GFSRIWVGHH YPVDVLGSLV VAIIIGFLFF RFSDLLRPFV DLVVRIYEAI 
181:	INKLTKKPTD QNF