TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
9.B.14.1.1









The cytochrome c biogenesis protein, CcmF
Bacteria
Proteobacteria
CcmF (Ccl1) of Rhodobacter capsulatus
9.B.14.1.2









The cytochrome c biogenesis protein, CycK
Bacteria
Proteobacteria
CycK of Bradyrhizobium japonicum
9.B.14.1.3









The cytochrome c biogenesis protein, CcmF
Bacteria
Proteobacteria
CcmF (CycK) of E. coli (P33927)
9.B.14.1.4









C-type biosynthesis protein, CcmF (620 aas; 17 TMSs) (resembles 9.B.67.3.3, and possibly APC family (2.A.3) members)

Eukaryota
Bangiophyceae
CcmF of Cyanidioschyzon merolae (Q9ZZP7)
9.B.14.1.5









Cytochrome C-type biogenesis protein, CcmF 

Archaea
Euryarchaeota
CcmF of Haloarcula marismortui (Q5V2F3)
9.B.14.1.6









Mitochondrial cytochrome C-type biogenesis protein, CcmF 

Eukaryota
Viridiplantae
CcmF of Arabidopsis thaliana (P93286)
9.B.14.1.7









Cytochrome biogenesis protein, CcmF (involved also in pyoverdine maturation (Baert et al. 2008).

Bacteria
Proteobacteria
CcmF of Pseudomonas aeruginosa
9.B.14.1.8









MURF1 protein of 443 aas and 16 TMSs

Eukaryota
Kinetoplastida
MURF1 of Leishmania tarentolae (Sauroleishmania tarentolae)
9.B.14.1.9









Putative XkR8 (TC family 2.A.112) homologue of 235 aas and 6 TMSs.

Bacteria
Proteobacteria
XkR8 homologue of Campylobacter jejuni
9.B.14.1.10









Uncharacterized protein of 796 aas and 19 TMSs

Bacteria
Spirochaetes
UP of Leptospira interrogans
9.B.14.1.11









Heme maturase of 518 aas and 13 TMSs, YejR

Eukaryota
Intramacronucleata
YejR of Tetrahymena thermophila
9.B.14.1.12









Uncharacterized protein of 285 aas and 6 TMSs

Eukaryota
Fungi
UP of Candida albicans
9.B.14.1.13









AgrC of 429 aas and 6 TMSs

Bacteria
Firmicutes
AgrC of Stahpylococcus epidermidis
9.B.14.1.14









Uncharacterized protein of 225 aas and 6 TMSs.

Bacteria
Thermotogae
UP of Petrotoga mobilis
9.B.14.1.15









Uncharacterized protein of 263 aas and 7 TMSs

Bacteria
Fusobacteria
UP of Fusobacterium nucleatum
9.B.14.1.16









Uncharacterized protein of 257 aas and 6 TMSs

Bacteria
Firmicutes
UP of Caldicellulosiruptor lactoaceticus
9.B.14.1.17









Uncharacterized protein of 434 aas and 7 TMSs.

Bacteria
Firmicutes
UP of Roseburia intestinalis
9.B.14.1.18









Uncharacterized GHKL domain-containing protein of 445 aas and 6 TMSs.

Bacteria
Firmicutes
UP of Clostridium hungatei
9.B.14.1.19









UP of 747 aas and 19 TMSs. Possibly related to 9.B.14.

Archaea
Candidatus Lokiarchaeota
UP of Lokiarchaeum sp GC14-75
9.B.14.1.20









Uncharacteerized ATP-binding protein of 424 aas and 7 N-terminal TMSs and a C-terminal hydrophilic domain.

Bacteria
Terrabacteria group
UP of Ruminococcus flavefaciens
9.B.14.2.1









The putative heme exporter, HelC
Bacteria
Proteobacteria
HelC of Rhodobacter capsulatus (P29961)
9.B.14.2.2









The putative heme exporter, CcmC (CycZ). This protein is also listed under TC# 3.A.1.107.1 as part of an ABC transporter
Bacteria
Proteobacteria
CcmC (CycZ) of Bradirhizobium japonicum (P30962)
9.B.14.2.3









The putative heme exporter, CycZ (CcmC)
Bacteria
Proteobacteria
CycZ (CcmC) of E. coli (P0ABM1)
9.B.14.2.4









Putative heme exporter, CcmC; also involved in pyoverdine maturation (Baert et al. 2008).

Bacteria
Proteobacteria
CcmC of Pseudomonas aeruginosa
9.B.14.2.5









ABC-type cytochrome c biogenesis putative heme transport system permease component C of 234 aas
Bacteria
Bacteroidetes/Chlorobi group
Putative ABC-type cytochrome c biogenesis transport system permease component of Melioribacter roseus
9.B.14.3.1









Cytochrome c biogenesis protein, CcsBA (936 aas; 10 TMSs; 14 TMSs predicted by the WHAT program (Frawley and Kranz, 2009).  May be a bifunctional protein with heme transport (export from the cytoplasm to the periplasm) and attachment to apocytochrome c (cytochrome c synthetase) activities.  Two heme binding sites have been identified in a homologue, one in the membrane and one on the external surface (on the periplasmic side of the membrane) (Sutherland et al. 2018).

Bacteria
Proteobacteria
CcsBA of Helicobacter hepaticus (Q7VHG9)
9.B.14.3.2









Cytochrome c biogenesis protein CcsA
Bacteria
Cyanobacteria
ccsA of Prochlorococcus marinus
9.B.14.3.3









Cytochrome c biogenesis protein CcsA or Ccs1 of 353 aas.  Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (Inoue et al. 1997).

Eukaryota
Viridiplantae
CcsA of Chlamydomonas reinhardtii
9.B.14.3.4









Cytochrome c biogenesis protein of 327 aas and 6 established TMSs, CcsA.

Bacteria
Actinobacteria
CcsA of Mycobacterium leprae
9.B.14.3.5









Membrane protein of 266 aas and 8 putative TMSs.

Bacteria
Proteobacteria
Membrane protein of Pseudomonas aeruginosa
9.B.14.3.6









Putative cytochrome c assembly protein, YpjD of 263 aas and 8 TMSs.  In an operon with YfjD, a putative Mg2+uptake protein (TC# 9.B.20.1.4).

Bacteria
Proteobacteria
YpjD of E. coli
9.B.14.3.7









Cytochrome c biogenesis protein, CcsA, of 309 aas and 8 TMSs.  May be a bifunctional protein with heme transport (export from the cytoplasm to the periplasm) and attachment to apocytochrome c (cytochrome c synthetase) activities.  Two heme binding sites have been identified in a homologue, one in the membrane and one on the external surface (on the periplasmic side of the membrane) (Sutherland et al. 2018).

Bacteria
Cyanobacteria
CcsA of Prochlorococcus marinus
9.B.14.3.8









Cytochrome c biogenesis protein, CcsA, of 309 aas and 8 TMSs.  May be a bifunctional protein with heme transport (export from the cytoplasm to the periplasm) and attachment to apocytochrome c (cytochrome c synthetase) activities.  Two heme binding sites have been identified in a homologue, one in the membrane and one on the external surface (on the periplasmic side of the membrane) (Sutherland et al. 2018).

Bacteria
Proteobacteria
CcsB of Helicobacter pylori
9.B.14.3.9









Cytochrome c biogenesis protein, CcsB, of 1041 aas and 14 TMSs.  May be a bifunctional protein with heme transport (export from the cytoplasm to the periplasm) and attachment to apocytochrome c (cytochrome c synthetase) activities.  Two heme binding sites have been identified in a homologue, one in the membrane and one on the external surface (on the periplasmic side of the membrane) (Sutherland et al. 2018).

Bacteria
Bacteroidetes
CcsB of Flavobacterium psychrophilum
9.B.14.3.10









Uncharacterized protein of 271 aas and 8 TMSs.

Bacteria
Planctomycetes
UP of Gemmataceae bacterium (freshwater metagenome)
9.B.14.4.1









XkR8 homologue of 383 aas and 11 TMSs.

Bacteria
Spirochaetes
XkR8 homologue of Brachyspira murdochii
9.B.14.4.2









Putative XkR8 homologue of 404 aas and 11 TMSs.

Bacteria
Spirochaetes
XkR8 homologue of Brachyspira pilosicoli
9.B.14.4.3









Putative XkR8 homologue of 587 aas and 12 TMSs.

Bacteria
Tenericutes
Putative XkR8 homologue of Mycoplasma mycoides
9.B.14.4.4









Uncharacterized protein of 431 aas and 5 TMSs in a 1 (N-terminal) + 4 (C-terminal) TMS arrangement.

Eukaryota
Apicomplexa
UP of Plasmodium yoelii
9.B.14.4.5









O-antigen polymerase of 439 aas and 10 TMSs.

Bacteria
Proteobacteria
Polymerase of Candidatus Pelagibacter
9.B.14.4.6









Uncharacterized protein of 497 aas and 12 TMSs.

Bacteria
Tenericutes
UP of Mycoplasma collis
9.B.14.5.1









Putative bacteriocin immunity protein of 572 aas and 14 putative TMSs.

Bacteria
Firmicutes
Imm protein of Bacillus cereus
9.B.14.5.2









Uncharacterized protein of 588 aas

Bacteria
Firmicutes
UP of Bacillus cereus