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9.B.14.2.3
The putative heme exporter, CycZ (CcmC)

Accession Number:P0ABM1
Protein Name:CcmC aka b2199 aka JW2187
Length:245
Molecular Weight:27885.00
Species:Escherichia coli [83333]
Number of TMSs:6
Location1 / Topology2 / Orientation3: Cell inner membrane1 / Multi-pass membrane protein2
Substrate ferroheme b

Cross database links:

RefSeq: AP_002795.1    NP_416703.1   
Entrez Gene ID: 946703   
Pfam: PF01578   
BioCyc: EcoCyc:CCMC-MONOMER    ECOL168927:B2199-MONOMER   
KEGG: ecj:JW2187    eco:b2199   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005886 C:plasma membrane
GO:0050662 F:coenzyme binding
GO:0015232 F:heme transporter activity
GO:0005515 F:protein binding
GO:0017004 P:cytochrome complex assembly
GO:0015886 P:heme transport
GO:0008535 P:respiratory chain complex IV assembly

References (4)

[1] “Escherichia coli genes required for cytochrome c maturation.”  Thoeny-Meyer L.et.al.   7635817
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “Global topology analysis of the Escherichia coli inner membrane proteome.”  Daley D.O.et.al.   15919996

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MWKTLHQLAI PPRLYQICGW FIPWLAIASV VVLTVGWIWG FGFAPADYQQ GNSYRIIYLH 
61:	VPAAIWSMGI YASMAVAAFI GLVWQMKMAN LAVAAMAPIG AVFTFIALVT GSAWGKPMWG 
121:	TWWVWDARLT SELVLLFLYV GVIALWHAFD DRRLAGRAAG ILVLIGVVNL PIIHYSVEWW 
181:	NTLHQGSTRM QQSIDPAMRS PLRWSIFGFL LLSATLTLMR MRNLILLMEK RRPWVSELIL 
241:	KRGRK