9.B.169.1.2
YeiB of 385 aas and 8 - 10 TMSs with a C-terminal DUF418 domain. It is encoded within an operon: yeiB-folE where FolE is GTP cyclohydrolase I, the first enzyme in the biosynthesis of tetrahydrofolic acid (El Yacoubi et al. 2006). Therefore YeiB could be a transporter of a derivative in the folate biosynthetic pathway (see also TC# 9.B.169.1.1).
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| Accession Number: | P25747 |
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| Protein Name: | Uncharacterized protein YeiB |
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| Length: | 385 |
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| Molecular Weight: | 43394.00 |
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| Species: | Escherichia coli (strain K12) [83333] |
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| Number of TMSs: | 9 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
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1: MERNVTLDFV RGVAILGILL LNISAFGLPK AAYLNPAWYG AITPRDAWTW AFLDLIGQVK
61: FLTLFALLFG AGLQMLLPRG RRWIQSRLTL LVLLGFIHGL LFWDGDILLA YGLVGLICWR
121: LVRDAPSVKS LFNTGVMLYL VGLGVLLLLG LISDSQTSRA WTPDASAILY EKYWKLHGGV
181: EAISNRADGV GNSLLALGAQ YGWQLAGMML IGAALMRSGW LKGQFSLRHY RRTGFVLVAI
241: GVTINLPAIA LQWQLDWAYR WCAFLLQMPR ELSAPFQAIG YASLFYGFWP QLSRFKLVLA
301: IACVGRMALT NYLLQTLICT TLFYHLGLFM HFDRLELLAF VIPVWLANIL FSVIWLRYFR
361: QGPVEWLWRQ LTLRAAGPAI SKTSR