TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
---|---|---|---|---|
9.B.217.1.1 | The PrsW intramembrane metaloprotease of 218 aas and 5 - 7 TMSs in a 1 + 4 or 1-7 TMS arrangement (see family description). | Bacteria |
Bacillota | PrsW of Bacillus subtilis |
9.B.217.1.2 | Membrane-spanning metaloprotease , PrsS of 415 aas and 8 TMSs. PrsS and σS function in a similar manner, and perhaps mediate virulence and resistance to DNA damage and cell wall-targeting antibiotics, via a common pathway (Krute et al. 2015). | Bacteria |
Bacillota | PrsS of Staphylococcus aureus |
9.B.217.1.3 | PrsW family intramembrane metalloprotease of 399 aas and 8 TMSs. | Bacteria |
Actinomycetota | PrsW of Agromyces aureus |
9.B.217.1.4 | PrsW transmembrane metaloprotease of 415 aas and 8 TMSs. PrsW regulates the activation of the ECF σ factor, CsfT and involved in the degradation of specific anti-sigma factors one of which is RsiT. It controls the resistance of C. difficile to antimicrobial peptides that are important for survival in the host (Ho and Ellermeier 2011). | Bacteria |
Bacillota | PrsW of Peptoclostridium difficile (Clostridium difficile) |
9.B.217.1.5 | PrsW family intramembrane metalloprotease of 234 aas and 7 TMSs. | Archaea |
Euryarchaeota | PrsW of Thermococcus nautili |
9.B.217.1.6 | PsrW family protease of 344 aas and 8 TMSs. | Archaea |
Euryarchaeota | PsrW of Haloarcula vallismortis |
9.B.217.1.7 | Uncharacterized PsrW family member of 757 aas and 13 TMSs. | Bacteroidota | PsrW homologue of Sporocytophaga myxococcoides | |
9.B.217.1.8 | Uncharacterized membrane metaloprotease of 222 aas and 7 TMSs. | Bacteria |
Candidatus Wolfebacteria | UP of Candidatus Wolfebacteria bacterium |
9.B.217.2.1 | Uncharacterized protein of 240 aas and 7 TMSs. | Archaea |
Candidatus Thermoplasmatota | UP of Aciduliprofundum boonei |
9.B.217.2.2 | Uncharacterized protein of 233 aas | Archaea |
Candidatus Thermoplasmatota | UP of Methanomassiliicoccus luminyensis |
9.B.217.2.3 | Uncharacterized Duf368 protein of 298 aas and 9 TMSs. | Bacteria |
Bacillota | UP of Peptoniphilus phoceensis |
9.B.217.2.4 | Uncharacterized protein of 239 aas and 7 TMSs. | Archaea |
Candidatus Thermoplasmatota | UP of Candidatus Methanoplasma termitum |
9.B.217.2.5 | DUF368 domain-containing protein of 265 aas and 7 or 8 TMSs. | Bacteria |
Thermotogota | DUF368 domain protein of Thermotoga neapolitana |
9.B.217.2.6 | DUF368 domain-containing protein of 337 aas and possible 9 or 10 TMSs in a potential 3 + 3 + 3 TMS arrangement. | Bacteria |
Spirochaetota | DUF368 domain protein of Treponema paraluiscuniculi |
9.B.217.2.8 | DUF368 domain protein of 350 aas and 9 or 10 TMSs. | Bacteria |
Actinomycetota | DUF368 protein of Corynebacterium efficiens |
9.B.217.2.9 | DUF368 domain protein of 299 aas and 8 TMSs in a 1 + 6 + 1 TMS arrangement. | Bacteria |
Bacteroidota | DUF368 protein of uncultured Cytophagia bacterium |
9.B.217.2.10 | DUF368 domain-containing protein of 286 aas and 9 (or 10) TMSs. | Bacteria |
Bacillota | DUF368 protein of Staphylococcus epidermidis |
9.B.217.2.11 | DUF368 domain-containing protein of 327 aas and 10 putative TMSs in a 2 + 7 + 1 TMS arrangement. | Archaea |
Euryarchaeota | DUF368 domain protein of Haloquadratum walsbyi |