TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
9.B.247.1.1









The cation-dependent mannose-6-phosphate receptor isoform 1 precursorof 277 aas and 1 TMS, M6PR, MPR46, MPRD.

Eukaryota
Metazoa
M6PR of Homo sapiens
9.B.247.1.2









The cation-independent mannose 6-phosphate receptor precursor, MPR or IGF2R, of 2491 aas and 2 TMSs.  MPR transports phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelysosomal compartment where the low pH causes dissociation of the complex. This receptor also binds IGF2. It acts as a positive regulator of T-cell coactivation by binding DPP4 (Ikushima et al. 2000).

Eukaryota
Metazoa
MPR of Homo sapiens
9.B.247.1.3









Cation-dependent mannose-6-phosphate receptor, M6PR, of 300 aas and 1 probable TMS.

Eukaryota
Metazoa
M6PR of Trachymyrmex septentrionalis
9.B.247.1.4









Uncharacterized protein of 291 aas and 1 probable TMS.

Eukaryota
Fungi
UP of Fusarium oxysporum (Fusarium vascular wilt)
9.B.247.1.5









Autophgy-like protein of 195 aas and 1 TMS.

Eukaryota
Viridiplantae
Autophagy-like protein of Arabidopsis thaliana (Mouse-ear cress)
9.B.247.1.6









Cation-independent mannose-6-phosphate receptor-like protein of 2389 aas and 2 TMSs, MPR.

Eukaryota
Metazoa
MPR of Sinocyclocheilus rhinocerous
9.B.247.1.7









Uncharacterized protein of 255 aas and 1 TMS.

Eukaryota
Dictyosteliales
UP of Dictyostelium discoideum (Slime mold)
9.B.247.1.8









Uncharacterized protein of 965 aas and 2 - 3 TMSs.  The first 360 aas resemble kinesin-1 (TC# 1.P.1.1.1) while the last 100 residues resemble the last 100 residues in other members of family 9.B.247 (The Mannose 6-P Receptor) Family, including the C-terminal 2 TMSs.

Eukaryota
Intramacronucleata
kinesin homologue of Paramecium tetraurelia
9.B.247.1.9









Uncharacterized protein of 275 aas and 2 - 3 TMSs.

Eukaryota
Kinetoplastida
UP of Trypanosoma cruzi