TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
9.B.282.1.1









Proteins of the iniBAC operon all give rise to multidrug resistance when mutated.  They may function with the MFS drug efflux pump, EfpA (TC# 2.A.1.3.78).  See family description for the evidence that ImiABC is involved in drug resistance (Colangeli et al. 2007). ImiA and ImiC have N-terminal regions that are homologous to each other. IniB is rich in glycines and shows apparent similarity to members of families 9.B.96, 1.B.89, 1.B.94 and 1.B.95, all of which may belong to the PE/PPE superfamily and are glycine-rich.  The apparent similarity may be an artifactual due the presence of redundant sequences of similar limited amino acid compositions.

Bacteria
Actinomycetota
IniABC of Mycobacterium tuberculosis
IniA, P9WJ99, 640 aas and 2 TMSs
IniB, P9WJ97, 479 aas and 4 TMSs
IniC, P9WJ95, 493 aas and 2 TMSs