9.B.97.7.1 The succinyl transferase, MdoC, OpgC or YmdD (formerly DUF418), is of 385 aas and 10 TMSs. Osmoregulated periplasmic glucans (OPGs) of E. coli are anionic
oligosaccharides that accumulate in the periplasmic space in response
to low osmolarity of the medium. Their anionic character is provided by
the substitution of the glucosidic backbone by phosphoglycerol
originating from membrane phospholipids and by succinyl residues
from an unknown origin. The mdoC gene is
within the mdoGH operon necessary for the synthesis of the
OPG backbone (Lacroix et al. 1999). The same is true for Rhodobacter spheroides in which in correspondng operon is the opgGIHC operon (Cogez et al. 2002).
|
Accession Number: | P75920 |
Protein Name: | Glucans biosynthesis protein C |
Length: | 385 |
Molecular Weight: | 44690.00 |
Species: | Escherichia coli (strain K12) [83333] |
Number of TMSs: | 10 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
|
---|
1: MNPVPAQREY FLDSIRAWLM LLGIPFHISL IYSSHTWHVN SAESSLWLTL FNDFIHSFRM
61: QVFFVISGYF SYMLFLRYPL KKWWKVRVER VGIPMLTAIP LLTLPQFIML QYVKGKAESW
121: PGLSLYDKYN TLAWELISHL WFLLVLVVMT TLCVWIFKRI RNNLENSDKT NKKFSMVKLS
181: VIFLCLGIGY AVIRRTIFIV YPPILSNGMF NFIVMQTLFY LPFFILGALA FIFPHLKALF
241: TTPSRGCTLA AALAFVAYLL NQRYGSGDAW MYETESVITM VLGLWMVNVV FSFGHRLLNF
301: QSARVTYFVN ASLFIYLVHH PLTLFFGAYI TPHITSNWLG FLCGLIFVVG IAIILYEIHL
361: RIPLLKFLFS GKPVVKREND KAPAR