| 1.A.153. The Putative Chemoreceptor (PCR) Family These protein are found in animals (Tardigrade, i.e., (Water bears), and are diverse in sequence, but they have the usual 2 or 3 + 2 + 2 + 1 TMS topology. They are presumed to resemble Odorant Receptors of TC family # 1.A.69 (Himmel et al. 2023). After two iterations with PSI-BLAST, members of family 1.A.69 come up in large numbers. | ||||
This family belongs to the Odorant Receptor Channel. | ||||
| References: | ||||
| Himmel, N.J., D. Moi, and R. Benton. (2023). Remote homolog detection places insect chemoreceptors in a cryptic protein superfamily spanning the tree of life. Curr. Biol. 33: 5023-5033.e4. | ||||
| Examples: | ||||
| TC# | Name | Organismal Type | Example | |
| 1.A.153.1.1 | Uncharacterized glustatory receptor of 554 aas and 7 TMSs in a 4 + 2 + 1 TMS arrangement (Himmel et al. 2023). | UGR of Remazzottius virieornatus (Water bear) (Tardigrade) | ||
| 1.A.153.1.2 | Uncharacterized protein of 486 aas and 7 TMSs in a 2 + 2 + 2 + 1 TMS arrangement. | UP of Hypsibius exemplaris | ||
| 1.A.153.1.3 | Uncharacterized protein of 491 aas and 8 putative TMSs in a 3 + 2 + 2 + 1 TMS arrangement. | UP of Paramacrobiotus metropolitanus | ||
| 1.A.153.1.4 | Uncharacteried protein of 457 aas and possibly 9 TMSs in a 2 + 3 + 2 + 2 TMS arrangement. | UP of Paramacrobiotus metropolitanus | ||
| 1.A.153.1.5 | Uncharacterized protein of 447 aas with 7 TMSs in a 4 + 2 + 1 TMS arrangement. | UP of Hypsibius exemplaris | ||