1.A.153. The Putative Chemoreceptor (PCR) Family  These protein are found in animals (Tardigrade, i.e., (Water bears), and are diverse in sequence, but they have the usual 2 or 3 + 2 + 2 + 1 TMS topology.  They are presumed to resemble Odorant Receptors of TC family # 1.A.69 (Himmel et al. 2023). After two iterations with PSI-BLAST, members of family 1.A.69 come up in large numbers.



This family belongs to the Odorant Receptor Channel.

 

References:

Himmel, N.J., D. Moi, and R. Benton. (2023). Remote homolog detection places insect chemoreceptors in a cryptic protein superfamily spanning the tree of life. Curr. Biol. 33: 5023-5033.e4.

Examples:

TC#NameOrganismal TypeExample
1.A.153.1.1

Uncharacterized glustatory receptor of 554 aas and 7 TMSs in a 4 + 2 + 1 TMS arrangement (Himmel et al. 2023).

UGR of Remazzottius virieornatus (Water bear) (Tardigrade)

 
1.A.153.1.2

Uncharacterized protein of 486 aas and 7 TMSs in a 2 + 2 + 2 + 1 TMS arrangement.

UP of Hypsibius exemplaris

 
1.A.153.1.3

Uncharacterized protein of 491 aas and 8 putative TMSs in a 3 + 2 + 2 + 1 TMS arrangement.

UP of Paramacrobiotus metropolitanus

 
1.A.153.1.4

Uncharacteried protein of 457 aas and possibly 9 TMSs in a 2 + 3 + 2 + 2 TMS arrangement.

UP of Paramacrobiotus metropolitanus

 
1.A.153.1.5

Uncharacterized protein of 447 aas with 7 TMSs in a 4 + 2 + 1 TMS arrangement.

UP of Hypsibius exemplaris