1.C.120 The Pore-forming Toxic Peptide, DinQ (DinQ) Family DinQ of E. coli is a small transmembrane toxic peptide located in the inner membrane. It's expression is controlled by AgrB antisense RNA and the repressor, LexA (SOS response regulator). Overexpression of dinQ mRNA leads to membrane depolaritzation and loss of cytoplasmic ATP (Weel-Sneve et al. 2013; Brielle et al. 2016). Pore formation is inferred.
References:
Brielle, R., M.L. Pinel-Marie, and B. Felden. (2016). Linking bacterial type I toxins with their actions. Curr. Opin. Microbiol. 30: 114-121. [Epub: Ahead of Print]
Weel-Sneve, R., K.I. Kristiansen, I. Odsbu, B. Dalhus, J. Booth, T. Rognes, K. Skarstad, and M. Bjørås. (2013). Single transmembrane peptide DinQ modulates membrane-dependent activities. PLoS Genet 9: e1003260.
Examples:
TC#	Name	Organismal Type	Example
1.C.120.1.1	*Pore-forming toxin, DinQ of 42 aas and 1 TMS (Brielle et al.* 2016).**		DinQ of E. coli

1.C.120.1.2	DinQ homologue of 37 aas with 1 TMS.		DinQ homologue of Pantoea stewartii

1.C.120.1.3	DinQ homologue of 62 aas and 1 TMS		DinQ homologue of Photorhabdus heterorhabditis

1.C.120.1.4	Uncharacterized peptide of 29 aas and 1 TMS.		UP of Xenorhabdus bovienii