1.D.109. The Lipid-Peptide Toroidal Pore (LPTP) Family

Semitoroidal pores form relatively easily in phosphatidyl inositol-containg membranes in which POPI molecules with a strong negative charge interact with peptide aggregates; a single peptide is unable to stabilize the semitoroidal pore (Ermakova et al. 2018).

References:

Ermakova, E., R. Kurbanov, and Y. Zuev. (2018). Coarse-grained molecular dynamics of membrane semitoroidal pore formation in model lipid-peptide systems. J Mol Graph Model 87: 1-10. [Epub: Ahead of Print]