1.E.37 The Phage T1 Holin (T1 Holin) Family

This family is represented in enterobacterial phages T1, RTP and F20 as well as Klebsiella phage KP36 and Escherichia phage ADB-2. All of these possess a putative holin that share a high level of identity. Additionally, Gp9 of E. coli phage phiE49 is similar in sequence. These proteins are short (55-71 aas) and have a single TMS (Catalão et al. 2012).


 

References:

Catalao MJ., Gil F., Moniz-Pereira J., Sao-Jose C. and Pimentel M. (2013). Diversity in bacterial lysis systems: bacteriophages show the way. FEMS Microbiol Rev. 37(4):554-71.
Examples:

TC#NameOrganismal TypeExample
1.E.37.1.1

Enterobacterial phage T1 holin, Gp13 of 71 aas and 1 TMS (Catalão et al. 2012).

Entrobacterial phage

Gp13 of enterobacterial phage T1

 
1.E.37.1.2

Gp9 holin (putative) of phage phiE49; 55 aas; 1 TMS

E. coli phage

Gp9 holin of E. coli phage phiE49

 
1.E.37.1.3

Holin of 71 aas and 1 TMS at about residue 30.

Holin of Klebsiella phage Shelby

 
1.E.37.1.4

Holin of 71 aas and 1 TMS at about residue 40.

Holin of Klebsiella phage Shelby