2.A.107 The MntP Mn2+ exporter (MntP) Family
The MntP (YebN) family (SwissProt family UPF0059) is a small family of prokaryotic (bacterial and archaeal) proteins of about 200 residues with 6 putative TMSs. CDD recognized two DUF204 repeats, each repeat having 3 TMSs. One member of the family has been shown to export manganese ions (Waters et al. 2011).
References:
The manganese ion efflux pump, MntP (YebN). Regulated by the MntR regulatory protein and the MntS sRNA (Waters et al., 2011). This family has been designated the DUF204 family.
Bacteria
YebN of E. coli
The Mth1812 of 184 aas and 6 TMSs.
Archaea
Mth1812 of Methanobacterium thermoautotrophicum
DUF204 homologue
Firmicutes
DUF204 homologue of Halobacillus halophilus
A manganese efflux pump of 184 aas and 6 TMSs.
Mn2+ exporter of Bacillus altitudinis
A manganese efflux pumpof 185 aas and 6 TMSs.
Mn2+ exporter of Bacillus subtilis
Hypothetical protein of 188 aas
Firmicutes
HP of Halanaerobium hydrogeniformans
Membrane protein of 210 aas
Firmicutes
Membrane protein of Bacillus subtilis