2.B.93.  The Trasferrin-mediated Heptapeptide-decorated Nanodrug (THN) Family

Transferrin (Tf) can promote the cellular transmembrane uptake of HAIYPRH (T7) peptide-conjugated nano-drugs. Zhang et al. 2023 demonstrated and confirmed the enhancing effect of Tf on HAIYPRH (T7)-decorated nano-drug transport. 



Zhang, X., M. Shan, S. Li, J. Zhao, X. Pang, G. Yang, and Y. Shan. (2023). Investigating the trans-membrane transport of HAIYPRH peptide-decorated nano-drugs. Phys Chem Chem Phys 25: 9766-9771.


TC#NameOrganismal TypeExample

Transferrin receptor protein 1, TFR1, of 760 aas.

TFR1 of Homo sapiens


Transferrin receptor protein 2,TFR2, of 801 aas.

TFR2 of Homo sapiens