9.B.30 The Xanthan Gum Polysaccharide Biosynthesis/Export, GumE (GumE) Family

GumE is a protein of 432 aas with 12 TMSs in a 5 + 4 + 3 TMS arrangement. it is involved, probably in a complex, in xanthan gum biosynthesis and export (Bianco et al. 2014). The family is diverse with proteins from many prokaryotes.  They may be exo-polysaccharide polymerases.



Bianco, M.I., M. Jacobs, S.R. Salinas, A.G. Salvay, M.V. Ielmini, and L. Ielpi. (2014). Biophysical characterization of the outer membrane polysaccharide export protein and the polysaccharide co-polymerase protein from Xanthomonas campestris. Protein Expr Purif 101: 42-53.


TC#NameOrganismal TypeExample

The xanthan gum biosynthetic/export protein, GumE of 432 aas and 12 TMSs in a 5 + 4 + 3 TMS arrangment (Bianco et al. 2014).


GumE of Xanthomonas campestris


Putative cell surface polysaccharide polymerase of 424 aas and 9 TMSs in a 4 + 3 + 2 TMS arrangement


GumE homologue of Marinobacter nanhaiticus