9.B.310. The Putative K+ Channel Protein (K+Ch) Family
A viral protein of 100 aas and 2 TMSs represent the founding member of this family. ORF A201L from chlorovirus NY-2A (accession #YP_001497468.1) was able to rescue a yeast mutant that lacked K+ uptake porters and channels. The results of these experiments suggested that this protein has K+ channel activity (Greiner et al. 2018). The positive rescue of growth by ORF A201L can be interpreted as evidence for a channel function for this protein. However, the electrophysiological characterization in HEK293 cells did not result in a robust K+ channel function (Greiner et al. 2018).
Putative K+ channel protein of 100 aas and 2 TMSs. Evidence has been presented that this protein may have K+ channel activity (Greiner et al. 2018).
K+ channel of chlorovirus NY-2A
Uncharacterized protein of 79 aas and 2 TMSs
UP of Candidatus Woesearchaeota archaeon CG1_02_33_12 (groundwater metagenome)
Uncharacterized protein of 78 aas and 2 TMSs.
UP of Candidatus Micrarchaeota archaeon
Uncharacterized protein of 73 aas and 2 TMSs.
UP of Orenia marismortui